Considering the advantages of using Brachial plexus nerve block to perform upper limb surgery and considering the importance of the type of drug used for intraoperative placement during blocking and increasing the duration of post-block analgesia, this study aimed to compare the effect of venous sedation with Dexmedetomidine and Propopoafol on the duration of Brachial plexus nerve block (supraclavecular technique) under ultrasound guidance in patients undergoing surgical procedure for upper extremity of Shariati Hospital. In this randomized, double blind clinical trial, 88 patients aged 20-50 years undergoing elective orthopedic surgery with ASA III, II, I, BMI below 35 and without a history of drug allergy, after receiving written consent, were divided into two groups of 44, and The start time of the sensory block, motion, and duration of the sensory block are compared to them. A group of supraclavicular injection of 25 ml of bupivacaine solution 0.5% and intravenous infusion of 0.5 mcg / kg / min of doxedetomidine, and the other group administered supraclavicular injection of 25 ml of bupivacaine 0.5% and intravenous infusion 50mcg / kg / min of propofol. The patient and anesthetist are not informed of the dual bundle form.
Then, the sensory and motor blocks are controlled at intervals of 5-10-15-30 minutes after injection and then every 10 minutes after surgery. The level of the sensory block of the nerve is measured by the pinprik test and the patient's question with the analogue speech scale (from 100% normal to 0% completely numb) and the motor block rate is graded from 0 to 5 by the Lovett-rating-scale.
The time of onset of the effect of the block of sensory and motor activity as the time between the completion of the last injection and the completion of the sensory and motor paralysis, the duration of the effect of the sensory block in the time between the completion of the sensory paralysis and the first postoperative pain, the duration of the motor block as the time between the completion of motion palsy and Movement power return is defined as normal.
A quantitative study of opioid use is performed by the PCA in a recovery room that contains 30mg of morphine sulfate in 30ml of normal saline. Every time the patient has pain, he injects 1mg of morphine and locks for 15 minutes.