The effect of early rehydration on fatigue and thirst in patients undergoing plasmapheresis

Evaluation of the effect of prehydration on the fatigue and exhaustion of patients undergoing plasma therapY

This cross-over interventional intervention is done. Patients undergoing Plasmapheresis are randomly assigned to one of two groups (first, a common fluid therapy, then a pre-term fluid therapy), or (b) an early treatment fluid, followed by a regular liquid therapy. At the start of the plasma milling and during it (by the researcher) and then (at home by a checklist that was previously trained to the patient by the method of completing it, until the next meeting is completed and will be delivered at the next meeting), the fatigue with The tool (RFS) and thirst are measured with the VAS visual simulation tool. In the usual fluid therapy, the plasma is first removed and the fluid is treated according to the protocol. In premature fluid therapy, 300 cc of the prescribed serum is first infused and the plasma is removed immediately, and the rest of the fluid is infused in accordance with the protocol during plasma therapy. This two-session procedure (each session is 2-4 hours) is repeated, and in the next two sessions, the fluid administration procedure is changed.

This cross-over interventional intervention is done. Patients undergoing Plasmapheresis are randomly assigned to one of two groups (first, a common fluid therapy, then a pre-term fluid therapy), or (b) an early treatment fluid, followed by a regular liquid therapy. At the start of the plasma milling and during it (by the researcher) and then (at home by a checklist that was previously trained to the patient by the method of completing it, until the next meeting is completed and will be delivered at the next meeting), the fatigue with The tool (RFS) and thirst are measured with the VAS visual simulation tool. In the usual fluid therapy, the plasma is first removed and the fluid is treated according to the protocol. In premature fluid therapy, 300 cc of the prescribed serum is first infused and the plasma is removed immediately, and the rest of the fluid is infused in accordance with the protocol during plasma therapy. This two-session procedure (each session is 2-4 hours) is repeated, and in the next two sessions, the fluid administration procedure is changed.

Inclusion criteria  The desire to participate in the study Age between 18-60 years Iranian nationality Alert Awareness of the person and time and place Use of the drug for a period of 4 hours before plasma therapy Have written consent to participate in the research. Ability to speak Persian   Literacy reading and writing According to the prescribing physician, you need to carry out plasma therapy Drug addiction Exit criteria Get sedative medications such as midazolam  Exercising physical activity or tolerating mental stress that causes fatigue Infections that cause weakness or fever like colds, allergies and ... Unwillingness to continue cooperation in the study Fewer than four sessions require plasma transcription Getting housing or sedation during the Plasmapheresis session

Group A Group b

Decrease fatigue Reduce thirst

Mashhad University of Medical Sciences