Comparison of the effectiveness of exposure and response prevention method and acceptance and commitment therapy on recovery of patients with obsessive-compulsive disorder receiving sertraline.

The purpose of the study: Comparative effects of exposure and response prevention and acceptance and commitment therapy among patients with obsessive-compulsive disorder receiving sertraline. Design of the study: An experimental design using pre and post-test and a three-month follow up was used. The study population: all patients referred to private and public institutions at Sanandaj city who are being diagnosed by obsessive-compulsive psychiatrists and are under medical treatment for this disorder. The sample includes 45 people. The sampling method is purposeful in a manner accessible, and random allocation based on block redundancy is carried out on 15 individuals per block and three blocks. The random allocation will be as follows: Persons who get the Yale Brown score of 16 or higher will enter Form 1 and will be entered in the same form if they have the exit criteria. If they do not have the exit criteria, they will be transferred to Form 2. Setting and conduct: After arranging patients in the three groups and taking written consent for entering to the research, pre-test is carried out and after that, both groups will be treated. Intervention group 1: Exposure and response prevention therapy that will be delivered through 12 sessions. Each session will take 45 minutes and will be held once a week. The patients will be treated by sertraline (50-200 mg/d) by the psychiatrist at the same time prescribed for 12 weeks. Intervention group 2: Acceptance and Commitment therapy that will be delivered through 12 sessions. Each session will take 45 minutes and will be held once a week. The patients will be treated by sertraline (50-200 mg/d) by the psychiatrist at the same time prescribed for 12 weeks. Control group: The patients in this group will receive one sertraline tablet (50-200 mg/d) under the supervision of psychiatrist for 12 weeks, then post-test will bw carried out at the end of therapy and 3 months later after the end of the therapy. Inclusion criteria: age between 18 and 60 years old; minimum level of the third grade at primary school; satisfaction with the company in the research; diagnosis OCD according to DSM5 criteria; receiveing the drug under the supervision of a psychiatrist; earn score 16 and over at Yale-Brown Obsessive Scale. Exclusion criteria: having severe personality disorder; psychotic symptoms (hallucination, delusions); having a physical illness; intellectual disability; Substance abuse. Intervention: Intervention included two groups of exposure and response prevention and acceptance and commitment therapy. Main outcome measures: Primary outcome measures will be OCD signs and symptoms. Secondary outcome measures will be subjective distress; obsessive rituals; control unwanted thoughts.

Vice chancellor for research, Kurdistan University of Medical Sciences and University of kurdistan.