The present study is a double-blind randomized (patient and researchers) clinical trial. The aim of this study was to determine and compare the effects of heparin 1000 and 5000 units on arterial blood gas findings with inclusion criteria, willingness to participate in The study was suitable for appropriate arterial blood supply, aged 18 to 70 years, traumatic patients undergoing mechanical ventilation up to one week, and exclusion criteria, inadequate blood supply to the site of bleeding, lesion or surgical shunt ( Presence of fistula in that limb), evidence of peripheral vascular disease in the area around the hand of the site of bleeding, the presence of coagulopathy or counter-treatments Moderate to high doses, other patients hospitalized in other parts, active infection in the arterial pathway, and any damage to the organs including fracture, dislocation, and burn, deterioration of the patient, death or discharge from the department, and trauma of the shelf Breast in the intensive care unit of the Shahid Beheshti Hospital, Sabzevar University of Medical Sciences in 1396 will be performed. In this study, arterial blood samples were collected from 152 samples (n = 76, n = 76, control group) from the research community. Blood samples were equally distributed (50 units) in two 100-unit insulin syringes impregnated with 1000 and 5000 heparin units, and then the samples were sent to the lab, after receiving the answer, compared with each other. In this study, the measured variables included heparin 1000 units, heparin 5000 units, and, PH, Pao2, Paco2, Hco3, BEe, Beb, Na, Ca, K.