Protocol summary

Study aim
The aim of this study is determining the effect of yoga exercises on quality of life and arm volume in women with post mastectomy lymphedema
Design
This is a double-blind, randomized controlled trial that will be conducted with a pilot basis on 40 eligible patients admitted to the Motahari clinic in Shiraz.
Settings and conduct
This study examines the effect of yoga on patients with secondary lymph edema following mastectomy surgery at the lymph edema clinic of Motahhari infirmary , Shiraz. During the research, participants and main investigators will be unaware of the initial allocation of individuals to the intervention and control groups. Therefore, the trial will be done in double-blinded design.
Participants/Inclusion and exclusion criteria
Inclusion Criteria: Having tendency to participate in the research; having the ability to communicate verbally for cooperation; Women with secondary upper limb lymph edema followed by mastectomy confirmed by the clinician; Possibility to use DVD at home; Ability to move independently without the need for auxiliary equipment; At least one year interval from mastectomy surgery to entering the research. Exclusion criteria: Unwillingness to cooperate; Establishing any condition that can lead to exacerbation of illness or hospitalization; The history of congestive heart failure or chronic obstructive pulmonary disease; Patients under chemotherapy or radiotherapy; Having pacemaker; Pregnancy.
Intervention groups
An 8-week yoga practice, based on specific protocol, in addition to the usual care is considered for the intervention group, and observation group will receive standardize routine care of clinic.
Main outcome variables
Changes in quality of life assessed by questionnaire , Changes in arm volume assessed by water displacement volume meter [ Time Frame: baseline, 4 weeks, and 8 weeks after the yoga intervention]

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20170925036390N1
Registration date: 2017-12-03, 1396/09/12
Registration timing: prospective

Last update: 2017-12-03, 1396/09/12
Update count: 0
Registration date
2017-12-03, 1396/09/12
Registrant information
Name
nazanin barshan tashnizi
Name of organization / entity
shiraz university of medical sciences
Country
Iran (Islamic Republic of)
Phone
+98 71 3628 9487
Email address
stud2281502694@sums.ac.ir
Recruitment status
Recruitment complete
Funding source
This study founding source is Deputy of Research and Technology of Shiraz University of Medical Sciences which is governmental .
Expected recruitment start date
2017-12-16, 1396/09/25
Expected recruitment end date
2018-02-19, 1396/11/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of Yoga exercise on quality of life and arm volume in women with post mastectomy Lymphedema
Public title
The effect of Yoga on women with post mastectomy Lymphedema
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Having tendency to participate in the research Having the ability to communicate verbally for cooperation Women with secondary upper limb Lymphedema followed by mastectomy confirmed by the clinician Possibility to use DVD at home Ability to move independently without the need for auxiliary equipment At least one year interval from mastectomy surgery to entering the research
Exclusion criteria:
Unwillingness to cooperate Establishing any condition that can lead to exacerbation of illness or hospitalization The history of congestive heart failure or chronic obstructive pulmonary disease Patients under chemotherapy or radiotherapy Having pacemaker Pregnancy
Age
From 18 years old to 85 years old
Gender
Female
Phase
N/A
Groups that have been masked
  • Participant
  • Care provider
  • Outcome assessor
  • Data analyser
Sample size
Target sample size: 40
Randomization (investigator's opinion)
Randomized
Randomization description
Samples will select according to study inclusion criteria and based on the target. Then they are randomly assigned to two groups using a random number table by block randomization method. First, researcher assistant writes all of the permutations A (representing the intervention group) and B (representing the control group), which consists of 6 different modes. Then, to allocate individuals with random number table, the finger moves randomly from a random point table to the row or column. If the number is between one and six, the permutation of that number is noted. For example, if the number 6 arrives, we will record ABAB permutations, and thus eligible patients will be in the control group and in the intervention group (yoga practice group)
Blinding (investigator's opinion)
Double blinded
Blinding description
This study will be performed in Double blind method so that the first researcher assistant contributes to the initial selection of patients, the completion of the questionnaire and random allocation, so the participants, investigator and even the care providers are unaware of the study groups. In this way, at the times of arm volume control and completing the questionnaire, the participants will not have any information about the allocation of the groups. Data will be imported and analyzed by a non-informed data analyzer, and ultimately the results of the final analysis will be communicated to the researchers.
Placebo
Not used
Assignment
Single
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Shiraz University of Medical Sciences
Street address
Shiraz, Zand Avenue, Central Building of the University of Medical Sciences
City
shiraz
Province
Fars
Postal code
713451978
Approval date
2017-09-23, 1396/07/01
Ethics committee reference number
IR.SUMS.REC.1396.108

Health conditions studied

1

Description of health condition studied
Postmastectomy lymphoedema syndrome
ICD-10 code
I97.2
ICD-10 code description
Postmastectomy lymphoedema syndrome

Primary outcomes

1

Description
Quality of Life
Timepoint
at baseline, 4 weeks, and 8 weeks after the intervention
Method of measurement
a specific quality of life assessment questionnaire for cancer patients

2

Description
arm volume
Timepoint
at baseline, 4 weeks, and 8 weeks after the intervention
Method of measurement
water displacement volumeter

Secondary outcomes

empty

Intervention groups

1

Description
The intervention of this study is yoga exercise for 8 weeks( 3 sessions in each week ). Two sessions of the weekly schedule will held in one hour at clinic training hall and under the supervision of the trained person and one session of it at home by pat
Category
Rehabilitation

2

Description
The observation group will receive standardize routine care of lymphedema clinic and will evaluate at three time steps.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Shiraz , Mottahari infirmary, Lymphedema clinic
Full name of responsible person
Dr.Zeinab Zakeri
Street address
Shiraz, Zand Avenue, Namazi Square, Shahid Motahari Clinic, 5th Floor
City
Shiraz
Province
Fars
Postal code
7193613111
Phone
+98 71 3612 1208
Email
zszakeri@sums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr. Seyed Basir Hashemi
Street address
Shiraz University of Medical Sciences, Zand street
City
Shiraz
Province
Fars
Postal code
713451978
Phone
+98 71 3235 7282
Email
hashemib@sums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shiraz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Nazanin Barshan Tashnizi
Position
MSc student in Medical_Surgical Nursing
Latest degree
Bachelor
Other areas of specialty/work
Nursery
Street address
Iran, Shiraz, Namazi Square, School of Nursing and Midwifery, Shiraz
City
Shiraz
Province
Fars
Postal code
7193613119
Phone
+98 71 3628 9487
Fax
Email
nbarshan72@gmail.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Dr. Niloofar Pasyar
Position
Assistant Professor(PHD)
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
School of Nursing and Midwifery, Namazi, Square Shiraz University of Medical Sciences Shiraz University of Medical Sciences Fars
City
shiraz
Province
Fars
Postal code
7193613119
Phone
+98 71 3647 4254
Fax
Email
npasyar@sums.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Nazanin Barshan Tashnizi
Position
MSc student in Medical_Surgical Nursing
Latest degree
Bachelor
Other areas of specialty/work
Nursery
Street address
Iran, Shiraz, Namazi Square, School of Nursing and Midwifery, Shiraz
City
Shiraz
Province
Fars
Postal code
7193613119
Phone
+98 71 3628 9487
Fax
Email
nbarshan72@gmail.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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