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Study aim
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Determine the efficacy of Thymoxymel with 10% thyme and Thymoxymel with 1.5 g thyme and 3 g thyme on weight loss in overweight people
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Design
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108 people who have been admitted to the study, who had been previously visited by the doctor, are divided into three groups of 36 members by randomly assigned random numbers.Blocked randomization is intended to ensure that exactly the same number of participants participates in consecutive but equal intervals, into three groups.The size of each block in this study is 36 We assign a number between 1 and 6 to each of the three permutations then we generate 36 random numbers in range 1 through 6 by RANDBETWEEN in Excel
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Settings and conduct
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108 patients who referred to university clinics who had studied in the study group were divided into 3 groups and To the first group, a normal oxymel with thyme flavor twice everyday 10 cc (as a placebo)To the second group, oxymel with 1.5 grams of thyme , twice everyday 10 cc,To the third group, oxymel with 3 grams of thyme , twice everyday 10 cc,The medication should be given to all three groups for a period of three months at monthly intervals.The shape and taste of all three types of medication are the same.During the study, all people, including doctors, patients, and the person in charge of delivery of the drug, will not be aware of the drug used.
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Participants/Inclusion and exclusion criteria
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inclusion criterea :
Body mass index (BMI) above 25 kg / m
Conscious Consent to Participate in the Study
Waist to hip ratio index (WHR) in men1 and women 0.9
Not taking any medications in the past month
exclusion criterea:
pregnancy
lactation
alcohol use
diabetes melitus
thymus allergy reaction history
acute or chronic liver disease
cancer
hypo or hyper thyroidism
renal failuer
Gastroesophageal reflux
Unwillingness of the patient to continue participating in the plan for any reason
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Intervention groups
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the first group, a normal oxymel with thyme flavor twice everyday 10 cc (as a placebo)To the second group, oxymel with 1.5 grams of thyme , twice everyday 10 cc,To the third group, oxymel with 3 grams of thyme , twice everyday 10 cc
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Main outcome variables
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Weight check in the first and the end of study , Abdominal circumference to hip circumference ratio check in the first and the end of study, BMI check in the first and the end of study , FBS check in the first and the end of study , Liver enzyme check in the first and the end of study, Lipid profile check in the first and the end of study