Investigating the Effects of a Herbal Mixture of tribulus terrestris, Silybum marianum ،Trigonella foenum-graecum and cinnamon zeylanicum on Blood Glucose in Type 2 Diabetes

Determine the effects of a herbal compound on the level of diabetes mellitus that can be used as a complementary therapy in diabetic patients.

In this study, 60 males and females with type 2 diabetes who are eligible to enter the study are selected. Participants are randomly divided into two intervention and control groups and assigned a code to hide the intervention group of each participant.

This clinical trial will be carried out before and after 60 men and women with type 2 diabetes. At the beginning of the study, patients receive fasting blood samples and their total cholesterol, LDL, VLDL, HDL, triglyceride, fasting blood glucose, hemoglobin glycosylated, liver enzymes, BUN, creatinine are examined. Patients are asked to take a tablespoon of herbaceous saccharine for 2 months. Fasting venous blood samples are tested at the end of the first month. Blood parameters will be measured using common kits in the market and autoanalysers. Patients participating in the research will not pay for the cost of the herb, visits, and tests. The third party encodes as experts, patients and medications so that the participant will be assigned to the allocation of clinical and clinical care groups to the patient and blind drug compounds.

The participants are 60 males and females with type 2 diabetes. Patients who are at high risk for not controlling glucose with a fixed dose of drug are excluded from this study.

Patients are asked to mix and take a tablespoon of herbal combination on a daily basis, twice before (before lunch and before dinner) with a glass of water and dough. A common diet for people with diabetes continues throughout the study. There is also a control group. In both groups, the usual hypoglycemic agents will continue throughout the study as in the previous procedure. Patients will be visited during the first week, and vital signs, glucose and possible side effects will be investigated. Fasting venous blood samples are tested at the end of the first month

TG, cholesterol, VLDL, HDL, LDL, fasting blood glucose, blood glucose two hours after food, glycosylated hemoglobin ALT, AST, blood creatinine, BUN.

En Given that the herbal drug and the drug are placed in the same full capsule, it is natural that the patient and the assessing physician are not aware of the type of medication they receive. Randomization is done based on the round-robin software and each patient will be treated or controlled in the group

A third person encodes as experts, patients, and medications so that the participant remains blind to the allocation of clinical and clinical care groups to the patient and drug compounds

Data and results will be published in the form of a paper after identification of the participants in the trial

After completing the sampling and analysis of the data and six months after the publication of the article

After the publication of this article, access to data is open to students and researchers

In order to produce a cheap and effective drug that can reduce the side effects of treatment in addition to improving blood glucose control by chemical agents. Data will be available if the mixture causes a decrease in blood glucose levels in diabetic patients.

Dr. Seyed Hadi Mousavi.Vakilabad Street. Mashhad Medical School. The first floor of the Pharmacology Department

Request is sent by e-mail. Or receive a data file by visiting Mashhad Medical School and during the administrative process of the Mashhad Medical Sciences Faculty