Protocol summary

Study aim
the purpose of this study is Comparing the effect of the transdiagnostic Therapy Based on emotion regulation with Religious / Spiritual Design versus the Barlow's transdiagnostic Therapy on Symptoms and general function in Women with Anxiety Disorders.
Design
in this research, 10 eligible women with one of the anxiety disorders referring to Mehre Shefa health center in Yazd were chosen and were randomly divided into two groups of treatment.
Settings and conduct
This research is performed in the Mehre Shefa health Center in Yazd. The participants in the research are unaware about type of treatment they recieved.
Participants/Inclusion and exclusion criteria
Entrance conditions: Female gender; Age of 18-30 years; Minimum high school diploma education; principal diagnosis of anxiety disorder based on DSM-5; Full satisfaction for attending sessions. Non-entrance Conditions: having Schizophrenia and other psychotic disorders; having Obsessive-compulsive disorder and related disorders; having Post traumatic stress disorder and related disorders; having Bipolar disorder and related disorders; having Substance and Alcohol abuse ; having substance/medication-induced anxiety disorder ; history of suicidal thoughts and attemps; taking medication or receiving psychotherapy during the last 6 months for the treatment of anxiety disorders.
Intervention groups
The two intervention groups consist of the transdiagnostic therapy based on emotion regulation with religious/spiritual design and Barlow's transdiagnostic therapy. Each treatment includes 12 one- hour sessions , which performed individually. in this study, no control group was used.
Main outcome variables
general symptoms of anxiety; General symptoms of depression; General function

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20180104038214N1
Registration date: 2018-08-08, 1397/05/17
Registration timing: retrospective

Last update: 2018-08-08, 1397/05/17
Update count: 0
Registration date
2018-08-08, 1397/05/17
Registrant information
Name
roghaye sadat mirjalili
Name of organization / entity
Tarbiat modares university
Country
Iran (Islamic Republic of)
Phone
+98 35 3521 1663
Email address
ra.mirjalili@modares.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-01-09, 1396/10/19
Expected recruitment end date
2018-02-08, 1396/11/19
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing the effect of the transdiagnostic therapy based on emotion regulation with religious/spiritual design versus Barlow transdiagnostic therapy on symptoms and general function in women with anxiety disorders
Public title
Comparing the effect of two transdiagnostic therapy on symptoms of anxiety disorders
Purpose
Other
Inclusion/Exclusion criteria
Inclusion criteria:
Female sex Age 18-30 years Have at least high school diploma Having one of the anxiety disorders based on DSM-5 Having full satisfaction to participate in sessions
Exclusion criteria:
Having schizophrenia and other psychotic disorders Having Obsessive-compulsive disorder and related disorders Having Post traumatic stress disorder and related disorders Having Bipolar mood disorder and related disorders Having substance and alcohol abuse Having substance/medication-induced anxiety disorder Having a history of suicidal thoughts and actions taking medication or receiving psychotherapy during the past 6 months for the treatment of anxiety disorders lack of religious adherence
Age
From 18 years old to 30 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 10
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization method: simple randomization through lottery Random unit: Individual
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
ethics comittee of Iran University of Medical Sciences
Street address
NO. 1., Mansoori ave., Niayesh street, Sattarkhan Blvd.
City
tehran
Province
Tehran
Postal code
۱۴۴۵۶۱۳۱۱۱
Approval date
2018-02-28, 1396/12/09
Ethics committee reference number
IR.IUMS.REC 1396.32515

Health conditions studied

1

Description of health condition studied
Phobic disorders
ICD-10 code
F40
ICD-10 code description
Phobic anxiety disorders

2

Description of health condition studied
generalized anxiety disorder
ICD-10 code
F41
ICD-10 code description
Other anxiety disorders

3

Description of health condition studied
panic disorder
ICD-10 code
F41
ICD-10 code description
Other anxiety disorders

Primary outcomes

1

Description
anxiety symptoms
Timepoint
before intervention, Sessions 3, 6, 9,12 of therapy and one-month and three-month follow-up
Method of measurement
Beck anxiety disorder, adult version of Screen for Child Anxiety Related Emotional Disorders (SCARED-A), generalized anxiety disorder scale- 7(GAD-7)

2

Description
general function
Timepoint
before intervention, Sessions 6, 12 of therapy and one-month and three-month follow-up
Method of measurement
Work and Social Adjustment Scale (WSAS)

Secondary outcomes

1

Description
depression status
Timepoint
2 stages in baseline, sessions 3, 6, 9, 12 and one-months and three-months follow-up
Method of measurement
beck depression inventory (BDI)

Intervention groups

1

Description
first Intervention group: transdiagnostic therapy based on emotion regulation with religious / spiritual design. The treatment protocol includes 12 one-hour session which run weekly and for three months. The titles of the sessions are, respectively, 1.the preparation for the treatment and enhance motivation of client, 2. understanding emotions in the balanced system of human, 3. introducing the role of cognition in regulating and modifying emotions to client, 4. identifying and modifying the god-images of client, 5. adapting the cognitive evaluations of client with god concept, 6. identifying the world- images of client and modifying them, 7. identifying the hereafter- images of client and modifying them, 8. behavioral self-caring, 9. awareness of physical feelings and reinforcement tolerance of them, 10.directing awareness to god, 11. Intrinsic and situation-based emotional exposure 12. relapse prevention
Category
N/A

2

Description
second Intervention group: Barlow transdiagnostic therapy. This intervention includes 8 modules, each module taking between one or two sessions. Modules include: 1. Increasing the motivation for participate in treatment, 2. Psychological training and seeking emotional experience, 3. Mindfulness-based emotional awareness, 4. Cognitive flexibility, 5. emotional avoidance and emotional behaviors, 6. awareness and tolerance of physical feelings, 7. Intrinsic and situation-based emotional exposure, 8. Prevention of relapse. sessions lengthen from 8 to 12 sessions and between approximately 50 to 60 minutes. sessions are held on a weekly basis.
Category
N/A

Recruitment centers

1

Recruitment center
Name of recruitment center
Mehre Shefa Health Center
Full name of responsible person
Hossein Mahdian
Street address
22 Bahman Blvd.
City
Yazd
Province
Yazd
Postal code
8917635195
Phone
+98 35 3526 2710
Fax
+98 35 3523 0145
Email
drmahdian100@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Kazem Malakouti
Street address
Rasool Akram hospital, Mansoory Ave. Sattarkhan Blvd
City
Tehran
Province
Tehran
Postal code
۱۴۴۵۶۱۳۱۱۱
Phone
+98 21 6650 9024
Email
kmalakouti@iums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Iran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tarbiat Modares university
Full name of responsible person
Roghaye Sadat Mirjalili
Position
Ph.D student
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
NO. 67 , Kargar ave, Yadavaran Blvd, Shahedie town
City
Yazd
Province
Yazd
Postal code
8943114386
Phone
+98 35 3521 1663
Fax
Email
ra.mirjalili@modares.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tarbiat Modares university
Full name of responsible person
Roghaye Sadat Mirjalili
Position
Ph.D student
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
NO. 67 , Kargar ave, Yadavaran Blvd, Shahedie town
City
YAZD
Province
Yazd
Postal code
8943114386
Phone
+98 35 3521 1663
Fax
Email
ra.mirjalili@modares.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Tarbiat Modares university
Full name of responsible person
Roghaye Sadat Mirjalili
Position
Ph.D student
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
NO. 67 , Kargar ave, Yadavaran Blvd, Shahedie town
City
YAZD
Province
Yazd
Postal code
8943114386
Phone
+98 35 3521 1663
Fax
Email
ra.mirjalili@modares.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Not applicable
Analytic Code
Not applicable
Data Dictionary
Not applicable
Title and more details about the data/document
All data is publishable after unrecognizing people. Designed protocol of transdiagnostic therapy based on emotion regulation with religious / spiritual design is Shareable. The data analysis plan includes visual charts in single case studies, and statistical indicators of Improvement percentages and effect sizes.
When the data will become available and for how long
6 months after the publication of results
To whom data/document is available
academic reasherchers
Under which criteria data/document could be used
treatment protocol can be used to evaluate its efficacy in other clinical groups and to compare its efficacy with other therapeutic protocols.
From where data/document is obtainable
roghaye sadat mirjalili mirjalili.r14@gmail.com
What processes are involved for a request to access data/document
The applicant must send an email in order to receive files and the documents and a request files will be sent for a maximum of two weeks.
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