Comparison of intravenous non-vented lidocaine effects in the relief of acute pain in extremity trauma patients

Comparison of intravenous morphine and nebulized lidocaine in acute pain relief in limb trauma patients.

In this study, 100 patients referred to the emergency department with severe acute traumatic trauma were examined. A single dose of nebulized lidocaine, 10 mg / kg, was administered to the intervention group. A single dose of intravenous morphine 0.1 mg / kg was administered to the control group. Patients are randomly divided into two groups by a statistician using statistical software.

In this study, 100 patients who referred to the emergency department with acute traumatic trauma were evaluated after obtaining consent, provided that they did not have any restrictions on the participation in the project. Patients were randomly assigned a 10 mg / kg lidocaine nebulizer or morphine Intravenous administration of 0.1mg / kg is prescribed and the severity of pain and vital signs of the patient is specified in minutes 0.10, 20.30, 60. Finally, we analyze the data.

Inclusion criteria : 1- Age over 16 years and under 65 years 2. Traumatic traumatic limbs require pain relief due to extreme pain in the limbs 3. Pain intensity greater than 5 based on NRS scale 4. Satisfaction to enter the study Exclusion criteria: 1. Disturbance of alertness 2. Hemodynamic impairment during injection of the drug 3. Drug or alcohol use, or pain relief or analgesics over the past 48 hours. 4. Lidocaine and morphine susceptibility 5. Chronic illnesses (heart disease, liver, biliary tract, kidney and lung) according to history and clinical examination. 6. No patient cooperation 7. No consent to enter the study

Intervention group:Prescribing nebulized lidocaine in patients with acute limb trauma. Control group:Prescribing intravenous morphine in patients with acute limb trauma.

The amount of pain

This study is a randomized, double blind clinical trial. All patients with entry criteria at the time of study are considered to be included in this study. After obtaining written consent and explaining the study conditions, patients are asked to rate their pain levels based on the NRS score. They then randomly enter each of the groups under review. The first group was treated with intravenous morphine (0.1 mg / kg, manufactured by Dr. Distribution Co., Tehran, Iran) and the second group with nevulose lidocaine (10mg / kg in saline (100 mg / ml concentration), Caspian Company Medicine, Rasht, Iran) were treated.

The grouping of patients will be based on Balanced Block Randomization in two groups A and B. Both the analgesic drugs are in boxes A and B, and only the physician responsible for the plan (supervisor) is aware of the drug content of each group. In the control group intravenous morphine is selected and at the same time is nebulized distilled water as placebo and in the intervention group,nebulized lidocaine, and at the same time, venous injection distilled water for patients will be prescribed. Then, for use by each supervisor, the numbering is done by the supervisor and what is mentioned in the office.