Inclusion criteria:
1. Signature of written consent for participation in the study
2-Age between 18-55 years
3-The presence of alopecia androgenetic in male or female
4-There is no other disorder that causes hair loss such as telogeny, echolinate or scarring hair (like lichen planus)
Class 1-4 in the Fitzpatrick Classification for Skin Type and Grade 3-6 Hair Loss for Men in the Norwood Hamilton Classification and Grade 2-3 Hair Loss for Women in the Ludwing Classification, Non-Use of Finasteride, Anti-Androgenetics, Local Estrogen , Progesterone, tamoxifen, anabolic steroids, potent potent medications for hyperkeratosis, oral glucocorticoid, lithium, phenothiazines within 3 months before the start of the study
Exclusion criteria:
1-Pregnancy
2-lactation
3-Using of anabolic steroids in the last 6month
4-Using of topical minoxidil in the last 6month
5-Using of antiandrogenetic drugs in the last 6 month
6-Using of the drugs who make hyper keratosis as like as systemic corticosteroids in the last 6 month
7-Dont be principled to curative protocol
8-Hair transplantation
9-Collagen vascular disease or HIV
10-Endocrinopathy like PCO, Hypotyroid