Protocol summary

Study aim
The effectiveness of mindfulness-based stress reduction on fatigue severity, functional disability and emotion dysregulation among patients with multiple sclerosis
Design
Randomization (random number table), without placebo control, single arm trial. The sample size of this study is 50 individuals: divided into 2 groups of 25 people.
Settings and conduct
Neyshabour society for support of patients with MS.
Participants/Inclusion and exclusion criteria
50 patients with Multiple Sclerosis referred to Neyshabour society for support of patients with MS. Inclusion criteria: Age of 20 to 55 years; Diagnosis of MS by a specialist; Having reading and writing skills; Passed at least 12-6 months from the onset of MS disease. Exclusion criteria: History of using psychiatric drugs; Mental retardation; Mental illness; History of drug abuse.
Intervention groups
Control group: Only for comparison with intervention group, no treatment is performed. Intervention group: 25 patients referring according to treatment protocol of mindfulness-based stress reduction (MBSR) are treated in 8 sessions. In order to be effective of before and after the intervention, and 2 months after the intervention, the measurements are carried out.
Main outcome variables
Fatigue Severity; Functional inability.

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20151228025732N33
Registration date: 2018-07-19, 1397/04/28
Registration timing: registered_while_recruiting

Last update: 2018-07-19, 1397/04/28
Update count: 0
Registration date
2018-07-19, 1397/04/28
Registrant information
Name
Alireza Emadi
Name of organization / entity
Semnan University of Medical Sciences, Semnan, Iran
Country
Iran (Islamic Republic of)
Phone
+98 23 3345 1336
Email address
are20935@semums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-02-13, 1396/11/24
Expected recruitment end date
2018-08-15, 1397/05/24
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effectiveness of mindfulness-based stress reduction on fatigue severity, functional disability and emotion dysregulation among patients with multiple sclerosis
Public title
The effectiveness of mindfulness-based stress reduction on fatigue severity, functional disability and emotion dysregulation among patients with multiple sclerosis
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Age of 20 to 55 years Diagnosis of MS by a specialist Having reading and writing skills Passed at least 12-6 months from the onset of MS disease
Exclusion criteria:
History of using psychiatric drugs Mental retardation Mental illness History of drug abuse
Age
From 20 years old to 55 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 50
Randomization (investigator's opinion)
Randomized
Randomization description
Block randomization; Individual; Random Number Tables. Randomized permutation blocks (block 2). Using Excel software to generate random number tables.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Neyshabur University of Medical Sciences
Street address
Neyshabur University of Medical Sciences, Moalem Square, Neyshabur
City
Neyshabur
Province
Razavi Khorasan
Postal code
9318614139
Approval date
2018-04-15, 1397/01/26
Ethics committee reference number
IR.NUMS.REC.1397.4

Health conditions studied

1

Description of health condition studied
Multiple Sclerosis
ICD-10 code
G35
ICD-10 code description
Multiple sclerosis

Primary outcomes

1

Description
Fatigue Severity
Timepoint
Before and after intervention and 2 months after intervention
Method of measurement
Fatigue Severity Questionnaire ( Fatigue Severity Scale (FSS))

2

Description
Functional inability
Timepoint
Before and after intervention and 2 months after intervention
Method of measurement
World Health Organization Disability Assessment Questionnaire

Secondary outcomes

empty

Intervention groups

1

Description
Control group: Only for comparison with intervention group, no treatment is performed.
Category
Diagnosis

2

Description
Intervention group:
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Neyshabour society for support of patients with MS
Full name of responsible person
Narges Ensan
Street address
Fazl Ibn Shazan Clinic, Fazl Street, Ferdowsi Street.
City
Neyshabur
Province
Razavi Khorasan
Postal code
9313833333
Phone
+98 51 4222 0408
Email
are20935@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Deputy of Research of Semnan University
Full name of responsible person
Eshagh Rahimian
Street address
Semnan University, Damghan 5 km Road, Semnan
City
Semnan
Province
Semnan
Postal code
3514799442
Phone
+98 23 3345 1336
Email
are20935@gmail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Deputy of Research of Semnan University
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Semnan University
Full name of responsible person
Eshagh Rahimian
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
Semnan University, Damghan 5 km Road, Semnan
City
Semnan
Province
Semnan
Postal code
3514799442
Phone
+98 23 3345 1336
Email
are20935@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Semnan University
Full name of responsible person
Eshagh Rahimian
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Psychology
Street address
Semnan University, Damghan 5 km Road, Semnan
City
Semnan
Province
Semnan
Postal code
3514799442
Phone
+98 23 3345 1336
Email
are20935@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Semnan University
Full name of responsible person
Narges Ensan
Position
Student
Latest degree
Master
Other areas of specialty/work
Psychology
Street address
Semnan University, Damghan 5 km Road, Semnan
City
Semnan
Province
Semnan
Postal code
3514799442
Phone
+98 23 3345 1336
Email
are20935@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
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