Dexamethasone Compared with Dexmedetomidine as an adjuvant to Bupivacaine for Supraclavicular Brachial Plexus Block

Dexamethasone Compared with Dexmedetomidine as an adjuvant to Bupivacaine for Supraclavicular Brachial Plexus Block

Double Blinded Randomized Clinical Trial

In the operating theater of Chamran hospital ,patients in the intervention group one receive 24 ml of bupivacaine(bupivacaine,Mylan,A.S.A, France)( 0.5%) plus 1 ml of dexamethasone (4 mg) for supraclavicular block. In the second group, patients receive 24 ml of bupivacaine (bupivacaine,Mylan,A.S.A, France)( 0.5%) plus 0.5 ml of doxedemotomidine (50 μg) for supraclavicular block.

Inclusion Criteria:Age 21 to 60 years old , Fractures of the forearm surgeries under supraclavicular plexus block. Exclusion Criteria: Heart disease ,Patients with high blood pressure, Bradycardia ,Hyperthyroidism ,Cardiac Blocks of Grade 1,2,3 ,Use of adrenoreceptor agonist and antagonist ,Peripheral neuropathy ,pregnant women, Patients who are addicted to narcotics and stimulant drugs ,Patients susceptible or allergic to the drugs , Coagulation disorders, Local infections, Patient refusal

Patients in the intervention group one receive 24 ml of bupivacaine(bupivacaine,Mylan,A.S.A, France)( 0.5%) plus 1 ml of dexamethasone (4 mg) for supraclavicular block. In the second group, patients receive 24 ml of bupivacaine (bupivacaine,Mylan,A.S.A, France)( 0.5%) plus 0.5 ml of doxedemotomidine (50 μg) for supraclavicular block.

Duration of sensory block, Onset of the sensory block,Duration of the motor block,Onset of the motor block

Due to several refereeing corrections at the time of registration, the expected recruitment start date has not been corrected in the last refereeing. Please, change expected recruitment start date two months later

Patients are randomly divided into two groups according to the table provided by Randomization.com and using Random permutations.

The same syringes containing 1 ml of dexamethasone or 1 ml of dexamethasone (0.5 cc dexamethasone diluted with half a cc distilled water), which are provided by a researcher, syringes are labeled only with the number, and the investigator dose not intervene in the Supraclavicular Brachial Plexus Block .