Protocol summary

Study aim
Comparison of Weight at the time of reach one, four, eight and discharge of hospital; Gestational Age at the time of reach one, four, eight and discharge of hospital; feeding progression and length of hospital stay between control group and intervention group.
Design
Clinical trials with intervention and control group; parallel group design; Double blind, and randomized
Settings and conduct
This study is related to oral motor skills and oral nutrition of premature infants. We have collected data in Akbarabadi and Arash Hospital in Tehran.. The infants were randomly assigned into two intervention and control groups. The intervention group received 5 minutes of oral massage daily. The doctor determined the amount and manner of receiving milk and the time of discharge. The doctor was unaware of the grouping of babies
Participants/Inclusion and exclusion criteria
Inclusion criteria: Premature infants with gestational age(GA) between 26-29 Physiological stability at the onset of intervention Parental consent Exclusion criteria: Failure to get gavage before the end of the 29th week (GA) chronic illness or genetic problems
Intervention groups
The intervention group received 5 minutes of oral massage per day for 10 days, according to Premature Infants Oral Motor Intervention (PIOMI) The control group only receives hospital routine services.
Main outcome variables
Feeding progression; Duration of transmission from oral gavage to full oral feeding; discharge from the hospital

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20180410039260N1
Registration date: 2018-07-06, 1397/04/15
Registration timing: retrospective

Last update: 2018-07-06, 1397/04/15
Update count: 0
Registration date
2018-07-06, 1397/04/15
Registrant information
Name
Hadise Ghomi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 7795 6924
Email address
Ha.ghomi@uswr.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2017-07-01, 1396/04/10
Expected recruitment end date
2017-11-21, 1396/08/30
Actual recruitment start date
2017-08-01, 1396/05/10
Actual recruitment end date
2017-12-21, 1396/09/30
Trial completion date
empty
Scientific title
Evaluation of the Premature Infant Oral Motor Intervention (PIOMI) on Oral Feeding Progression in Preterm Infants With Gestational Age between 26-29weeks.
Public title
evaluation of PIOMI on oral feeding in preterm infants
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Premature infants with gestational age between 26-29 weeks Physiological stability at the onset of intervention Apgar score higher than 6 in the fifth minute after birth Parental consent
Exclusion criteria:
Chronic genetic and medical problems Parental dissatisfaction No received of nutrition through gavage until the end of the 29th week of GA
Age
From 182 days old to 203 days old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Outcome assessor
Sample size
Target sample size: 30
Actual sample size reached: 30
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization is simple and using the https://www.randomizer.org site.
Blinding (investigator's opinion)
Double blinded
Blinding description
infants mothers and doctors The doctor examines the oral and nutritional capacity.The doctor does not know about the grouping of infants.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of university of social walfare and rehabilitation science
Street address
University of social walfare and rehabilitation science, Koodakyar Ave, Daneshju blv, Evin, Trlehran
City
Tehran
Province
Tehran
Postal code
۱۹۸۵۷۱۳۸۳۴
Approval date
2017-06-18, 1396/03/28
Ethics committee reference number
IR.USWR.REC.1396.85

Health conditions studied

1

Description of health condition studied
Feeding in Premature infants
ICD-10 code
P92
ICD-10 code description
Feeding problems of newborn

Primary outcomes

1

Description
Feeding progression was calculated from the day when oral feedings were initiated to the day when full oral feedings were attained. Fewer days indicated faster progression.
Timepoint
postmenstrual age(PMA) on the time of one, fore and full oral feeding
Method of measurement
PMA , days

2

Description
Length of hospital stay
Timepoint
Gestational age in birth time and discharge time (day)
Method of measurement
Day

Secondary outcomes

1

Description
Weight on the time of one, fore and full oral feeding and discharge
Timepoint
Time of one, fore and full oral feeding and discharge
Method of measurement
Digital Balance in grams

Intervention groups

1

Description
Intervention group:5 Minute massage in and around the mouth using a PIOMI protocol, once a day for ten days
Category
Rehabilitation

2

Description
Control group: Medical and nursing services provided in all hospitals. There is no speech therapy intervention in these two hospitals
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
بیمارستان اکبرآبادی
Full name of responsible person
Ali Mazoury
Street address
Akbarabadi Hospital, Raees Abdollahi Street, Molavi street
City
Tehran
Province
Tehran
Postal code
1168743514
Phone
+98 21 5560 6034
Email
hh.ghomi@yahoo.com

2

Recruitment center
Name of recruitment center
Arash hospital
Full name of responsible person
Shahin Nariman
Street address
Eastern 162th St, Baghdarnia st, Resalat Highway, Tehranpars, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1646745613
Phone
+98 21 7788 3284
Fax
+98 21 7788 3196
Email
hh.ghomi@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Fariba Yadegari
Street address
Kodakyar Ave, Daneshjo Blvd, Evin
City
Tehran
Province
Tehran
Postal code
1985713834
Phone
+98 21 2221 8008
Fax
+98 21 2218 0121
Email
hh.ghomi@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
University of social welfare and rehabilitation sciences
Proportion provided by this source
50
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Hadise Ghomi
Position
Master student of speech therapy
Latest degree
Bachelor
Other areas of specialty/work
Speech therapy
Street address
Kodakyar Ave, Daneshjo Blvd ,Evin
City
Tehran
Province
Tehran
Postal code
1985713834
Phone
+98 21 2221 8008
Email
hh.ghomi@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Hadise Ghomi
Position
Master student of speech therapy
Latest degree
Bachelor
Other areas of specialty/work
Speech therapy
Street address
Koodakyar Ave, Daneshjo Blvd, Evin
City
Tehran
Province
Tehran
Postal code
1985713834
Phone
+98 21 2218 0083
Email
hh.ghomi@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
University of social welfare and rehabilitation sciences
Full name of responsible person
Hadise Ghomi
Position
Master student of speech therapy
Latest degree
Bachelor
Other areas of specialty/work
Speech therapy
Street address
Koodakyar Ave, Daneshjo blvd, Evin
City
Tehran
Province
Tehran
Postal code
1985713834
Phone
+98 21 2218 0083
Email
hh.ghomi@yahoo.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Not applicable
Title and more details about the data/document
Unidentifiable infants data, summary of treatment protocol, statistical analysis will be fully published.
When the data will become available and for how long
From 2018
To whom data/document is available
Everyone interested in this topic
Under which criteria data/document could be used
There are no special conditions
From where data/document is obtainable
Researcher email address: hh.ghomi@yahoo.com
What processes are involved for a request to access data/document
There is no particular process. After receiving the email, the information will be sent.
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