Comparison of effect of ringer's solution and lactated ringer as prime solution on acidosis and lactate level in noncyanotic pediatric cardiac surgery

effect of ringer and lactated ringer as prime solution on acidosis and lactate level in noncyanotic pediatric cardiac surgeries

50 children undergoing open heart surgery are randomly divided into two groups.This clinical trial with two parallel groups will be double blinded.

This study will be conducted in the operating room of Shahid Rajaee Heart Center and patients and the surgical team will be unaware of the type of solution used.

Inclusion criteria:Children with non-cyanotropic heart disease, Having consent from the parents of the patient, Non-emergency surgery, Absence of coagulation disorders. Absence of anemia (hemoglobin less than 10 g / dl), Absence of hepatic impairment, Absence of kidney failure, Absence of lung failure, Absence of diabetes, Absence of acid disorder and severe preoperative hypertension, Lactate levels greater than 2 mM per liter before surgery, Not having a history of heart surgery (redo) Exclusion criteria:Periods of arterial blood pressure reduction before surgery, Ultrafiltration during bypass

Intervention group, lactated ringer 350 to 400 cc, once at onset bypass. Control group, Ringer's solution 350 to 400 cc, once at onset bypass.

The variables of pH, Bicarbonate, Base Excess, Chloride, Lactate and the amount of sodium bicarbonate injected will be recorded.

Simple randomization, lottery through sealed envelopes

Participating patients,Responsible perfusionist and Responsible for data collection were kept blind.

Patient privacy