Protocol summary

Study aim
The effect of Diltiazem gel in camparison with Lidocaine gel on the pain parameter in rectosigmoidoscopy without sedation
Design
In this research, 80 eligible patients needed rectosigmoidoscopy referring to Qom gastroenterology clinic were chosen. Then, patients by block randomization were randomly divided into two control and intervention groups.
Settings and conduct
The study was performed as a randomized clinical trial at Shahid Beheshti Hospital in Qom. The study is double-blinded, and intervention is conducted by someone other than the care provider, and care provider and participants is unaware of the type of treatment.
Participants/Inclusion and exclusion criteria
People entering the study aged 18 to 40 years and patients who have need general anesthesia were not included in the study
Intervention groups
Intervention group will receive the Diltiazem gel, 2cc, once, 5 minutes before rectosigmoidoscopy, rectal injection and control group will receive Lidocaine gel, 2cc, once, 5 minutes before rectosigmoidoscopy, rectal injection
Main outcome variables
Pain scale during rectosigmoidoscopy

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20161205031252N6
Registration date: 2018-05-26, 1397/03/05
Registration timing: registered_while_recruiting

Last update: 2018-05-26, 1397/03/05
Update count: 0
Registration date
2018-05-26, 1397/03/05
Registrant information
Name
Ahmad Hormati
Name of organization / entity
Qom university of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 25 3612 2053
Email address
hormatia@muq.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-05-22, 1397/03/01
Expected recruitment end date
2018-08-23, 1397/06/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of Diltiazem gel in camparison with Lidocaine gel on the pain parameter in rectosigmoidoscopy without sedation
Public title
The effect of Diltiazem gel and Lidocaine gel on the pain of rectosigmoidoscopy
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Age 18 to 40 years Need to rectosigmoidoscopy Would like to participate in the study
Exclusion criteria:
Anal fissure Need general anesthesia
Age
From 18 years old to 40 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Participant
  • Care provider
  • Outcome assessor
Sample size
Target sample size: 80
Randomization (investigator's opinion)
Randomized
Randomization description
block randomization at the level of the individual
Blinding (investigator's opinion)
Double blinded
Blinding description
participants and the therapist does not know the allocation of people, and only the person who supplies the medication to the patients is aware of the type of allocation
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Qom University of Medical Sciences
Street address
No. 83, 4th alley, 1.1 alley, Safashahr Blvd
City
Qom
Province
Ghoum
Postal code
3716987366
Approval date
2018-05-01, 1397/02/11
Ethics committee reference number
IR.MUQ.REC.1397.011

Health conditions studied

1

Description of health condition studied
Gastrointestinal bleeding
ICD-10 code
K92.2
ICD-10 code description
Gastrointestinal hemorrhage, unspecified

Primary outcomes

1

Description
Pain scale
Timepoint
ِDuring rectosigmoidoscopy
Method of measurement
Visual Analogue Scale

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Diltiazem gel, 2cc, once, 5 minutes before rectosigmoidoscopy, rectal injection
Category
Treatment - Drugs

2

Description
Control group: Lidocaine gel, 2cc, once, 5 minutes before rectosigmoidoscopy, rectal injection
Category
Treatment - Drugs

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Beheshti Hosbital
Full name of responsible person
Ahmad Hormati
Street address
Shahid Beheshti Hospital, Shahid Beheshti Blvd, Azadegan Square.
City
Qom
Province
Ghoum
Postal code
3719964797
Phone
+98 25 3612 2824
Email
hormatia@muq.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Hosein Saghafi
Street address
Namber 83, Alley 4, Alley 1.1, Safashahr Street
City
Qom
Province
Ghoum
Postal code
3716987366
Phone
+98 25 3285 2720
Email
hormatia@muq.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ghoum University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Ahmad Hormati
Position
Assistant Professor
Latest degree
Subspecialist
Other areas of specialty/work
Internal Medicine
Street address
Gastroenterology and Hepatology Disease Research Center, Endoscopy Unit, Shahid Beheshti Hospital, Shahid Beheshti Blv, Qom
City
Qom
Province
Ghoum
Postal code
3719964797
Phone
+98 25 3612 2053
Fax
+98 25 3612 2053
Email
Hormatia@muq.ac.ir
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Ahmad Hormati
Position
Assistant Professor
Latest degree
Subspecialist
Other areas of specialty/work
Internal Medicine
Street address
Gastroenterology and Hepatology Disease Research Center, Endoscopy Unit, Shahid Beheshti Hospital, Shahid Beheshti Blv, Qom
City
Qom
Province
Ghoum
Postal code
3719964797
Phone
+98 25 3612 2053
Fax
+98 25 3612 2053
Email
Hormatia@muq.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Ghoum University of Medical Sciences
Full name of responsible person
Ahmad Hormati
Position
Assistant Professor
Latest degree
Subspecialist
Other areas of specialty/work
Internal Medicine
Street address
Gastroenterology and Hepatology Disease Research Center, Endoscopy Unit, Shahid Beheshti Hospital Qom, Shahid Beheshti Blv, Qom
City
Qom
Province
Ghoum
Postal code
3719964797
Phone
+98 256122053
Fax
Email
Hormatia@muq.ac.ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
The data are specific to this study
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
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