Evaluating the effect of injection of ketorolac or dexamethasone into the ptrygomandibular space on pain and swelling following removal of third mandibular molar

Evaluating the effect of injection of ketorolac or dexamethasone intothe ptrygomandibular space on pain and swelling following removal of lower third mandibular molar

Randomized clinical trial using randomization method with sample size of 60, blind, phase 2

The population of patients referring to Kerman University of Medical Science, Dentistry Faculty in order to have a surgery to remove their impacted wisdom tooth or third molar (M3) are randomly divided into two groups. After injecting the anesthetic substance, one of the two materials is injected into petrigom andibuler space. Before commencing on the surgery, a ruler is used to measure the mouth opening right from the tip of incisor teeth. After the surgery, a check list designed based on VAS criteria is used to document the patients’ pain and discomfort right after the surgery, one, three and six hours after the surgery and finally on a daily basis. This process continues for one week. After a week, the mouth opening measurement is done once again for every patient. The number of times and the time each patient has used the painkiller is also recorded.

The subjects entering this study include all those patients in need of one-sided Third Molar (M3) surgery, with the age of more than 18 years, and a weight lower than 100 kg and be in the category of ASA 1, 2. the patients who have used painkiller 24 hours before treatment and who have shown sensitivity toward the injected medicines or have received more than three anesthetic injection.

A group that receives dexamethasone. A group that receives ketorolac

Severity of pain, severity of discomfort, oral opening, side effects, pain reliefs,Intervals between pain relief

In this study, 60 identical sheets (30 sheets for Dexamethasone and 30 sheets for Ketorolac) are deposited in a container and the sheets are randomly removed without replacement from the container. And it continues until all the papers are taken.

Only a nurse is aware of the type of injectable drug. The surgeon and the patient are unaware of the injected medication and the nurse gives the medication to surgeon.

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