Determination of the effect of light blue reinforcement intervention on oxidative stress biomarkers in petrochemicals control room shift workers
Design
This is a pre and post-interventional study and is designed in three phases.
Settings and conduct
The present study population included all individuals in the control rooms of a petrochemical industry. The exclusion criteria of the study were suffering from underlying diseases, such as diabetes, cardiovascular disease, and hypertension, and doing heavy sports. The participants were required to sign written informed consent forms and complete the demographic characteristics questionnaire. Saliva samples were collected from the participants at the end of the work shifts before and after the intervention. Then, oxidative damage parameters, including total antioxidant capacity of saliva, thiol groups, and catalase enzyme, were measured using FRAP (12), HU (13), and Abi (14) methods, respectively. The intervention involved changing the color temperature of the work environment, which was performed by replacing the conventional fluorescent lamps (3000 °K) with fluorescent lamps with a color temperature of 17000 °K. The effect of the intervention was assessed after one month.
Participants/Inclusion and exclusion criteria
Age under 45 years old; having general health
Intervention groups
Intervention in this scheme is a change in brightness and is used for lighting with different color temperatures. The use of any type of lighting system is one week for each time.
Main outcome variables
Total antioxidant capacity of saliva using FRAP and thiol groups by HU and catalase enzyme by ABI
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20180925041131N1
Registration date:2018-10-12, 1397/07/20
Registration timing:retrospective
Last update:2018-10-12, 1397/07/20
Update count:0
Registration date
2018-10-12, 1397/07/20
Registrant information
Name
reza kazemi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 71 3725 1002
Email address
reza_kazemi2007@yahoo.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-06-22, 1397/04/01
Expected recruitment end date
2018-09-23, 1397/07/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of light’s color tempereture on antioxidative biomarkers in petrochemicals control room shift workers
Public title
The effect of light’s color tempereture on antioxidative biomarkers
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
Having general health
Being under the age of 45 years
Exclusion criteria:
Metabolic diseases
Exercise and heavy activity 24 hours before study
Age
To 45 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Shiraz University of Medical Sciences
Street address
Shiraz University of Medical Sciences, Zand St.
City
Shiraz
Province
Fars
Postal code
71645111
Approval date
2018-05-09, 1397/02/19
Ethics committee reference number
IR.SUMS.REC.1397.141
Health conditions studied
1
Description of health condition studied
Oxidative stress
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Total antioxidant capacity of saliva
Timepoint
Before intervention and after a month of intervention
Method of measurement
The total antioxidant capacity of saliva is measured using the FRAP method
2
Description
Thiol groups
Timepoint
Before intervention and after a month of intervention
Method of measurement
HU method
3
Description
Catalase enzyme
Timepoint
Before intervention and after a month of intervention
Method of measurement
ABI method
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: the type of intervention in this study is a light source with a color temperature of 17,000 Kelvin and 6500 Kelvin. The duration of the intervention for each light source is one month. Before intervention and after a month of intervention, total antioxidant capacity of saliva, catalase enzyme and thiol groups are measured and compared.
Category
Prevention
Recruitment centers
1
Recruitment center
Name of recruitment center
Zagross petrochemicals
Full name of responsible person
Mohamad Zahedi
Street address
Persian golf blvd., Zagross Petrochemicals company
City
Asalueh
Province
Fars
Postal code
715679421
Phone
+98 77 3732 3330
Fax
+98 77 3732 3207
Email
reza_kazemi2007@yahoo.com
Web page address
http://www.zpcir.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Younes Ghasemi
Street address
Razi Blv, school of health
City
Shiraz
Province
Fars
Postal code
23454321222
Phone
+98 71 3725 1001
Fax
+98 71 3725 1002
Email
reza_kazemi2007@yahoo.com
Web page address
https://sums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
No
Title of funding source
Vice chancellery for research affairs of Shiraz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Reza Kazemi
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Ergonomics
Street address
School of Public Health, Razi Blvd., Shiraz
City
Shiraz
Province
Fars
Postal code
75345r678909
Phone
+98 71 3725 1001
Email
reza_kazemi2007@yahoo.com
Web page address
https://sums.ac.ir
Person responsible for scientific inquiries
Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Reza Kazemi
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Ergonomics
Street address
School of Pubic Health, Razi Blvd., Shiraz
City
Shiraz
Province
Fars
Postal code
76564678990
Phone
+98 71 3725 1001
Email
reza_kazemi2007@yahoo.com
Person responsible for updating data
Contact
Name of organization / entity
Shiraz University of Medical Sciences
Full name of responsible person
Reza Kazemi
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Ergonomics
Street address
School of Public Health, Razi Blvd., Shiraz
City
Shiraz
Province
Fars
Postal code
34234345456
Phone
+98 71 3725 1001
Email
reza_kazemi2007@yahoo.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Not applicable
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available