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Study aim
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This study aimed to evaluate the impact of short term and mid-term prophylactic appendectomy during laparoscopic surgery in patients with endometriosis.
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Design
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This randomized double-blind clinical trial, including 56 female patients with endometriosis, candidates for laparoscopic surgery will take place in Hazrat e Rasool hospital-Tehran. individuals will be divided randomly using random digits table in two equal groups (n1=n2=28).
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Settings and conduct
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After obtaining written informed consent, both groups will receive a prophylactic antibiotic prior to the surgery and then under general anesthesia, the intervention will be performed. In the intervention group, the appendix will be removed prophylactically during laparoscopic surgery for endometriosis.
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Participants/Inclusion and exclusion criteria
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Patients with endometriosis, laparoscopic surgery candidates, no history of appendectomy, informed consent form included in the study. exclusion criteria were considered as gastrointestinal endometriosis, acute appendicitis, pelvic pain with ethology other than endometriosis, Failure to prove the presence of endometriosis in surgery, unwillingness to continue the study and abnormal anatomical placement of appendix.
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Intervention groups
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The first group will undergo appendectomy with laparoscopy surgery and the second group will exclusively undergo laparoscopy surgery without appendectomy. two groups will compare with each other regarding short term consequences (duration of surgery, Lost blood volume, duration of hospitalization, complications after surgery in the hospital, The need for admission of analgesics during hospitalization) and also mid-term consequences (complications of 6 months after surgery, mid-term admission or hospitalization).
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Main outcome variables
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Duration of hospitalization, lost blood volume, pain, fever, morbidity, histopathological findings in appendices