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Study aim
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Determination of Tranexamic Acid Effects and Its Complications in Prevention of Gestation During and After Cesarean Section
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Design
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In this study, the prevalence of patients who were candidates for cesarean section in 2019-2020 was initially readily available or available to eligible individuals up to the time of reaching the sample of 100 people. Then, using randomized block method, two groups And they are divided into the group of tranexamic acid and the control group is given normal saline.
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Settings and conduct
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In this single-blinded study that is done in Imam Ali Hospital, Zahedan, candidates for cesarean section divide into two groups of case and control by random block method. The case group is treated with Tranexamic Acid and the control group is given normal saline. Hemoglobin and gases used during the surgery measure before and six hours after surgery. Candidates evaluate during admission, during cesarean section and 6 weeks after cesarean section through a complications checklist.
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Participants/Inclusion and exclusion criteria
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Exclusion Criteria: High Body Index, History of venous thrombosis, Uterian myoma, liver and kidney disease, History of High Birth weight, Placenta Previa, Acreta, Pre Eclampsia, Disseminated Intravascular Coagulation
Inclusion Criteria: All women who are candidates for cesarean section.
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Intervention groups
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Intervention group: In this group, patients who are candidates for cesarean section are given10 mg/kg tranexamic acid before surgery and Drug effects and complications are reviewed 6 weeks later.
Control group: In this group, patients who are candidates for cesarean section are given a 10 mg/kg Normal saline before surgery and complications are reviewed 6 weeks later.
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Main outcome variables
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Hemoglobin measure before and six hours after surgery, Counting the gases used during the surgery