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Study aim
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Clinical, histologic and histomorphometric determine and comparison of Ceno Bone ® with and without plasma rich growth factor in dental socket
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Design
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Clinical trials with a control group, with parallel groups,
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Settings and conduct
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The study will be conducted on patients referring to the periodontics department of Babol Dental School, which has a molar un-restorable tooth in the mandible. Sampling was done randomly and for each treatment group, 10 samples and a total of 20 samples were considered. Participants and outcome measurer of this study are blind (double-blind).
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Participants/Inclusion and exclusion criteria
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Dental Infection, Patients with gingivitis or active untreated periodontitis, Patients with ankylosis of teeth, bone with dehiscence, Diseases that affect tissue repair.
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Intervention groups
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1.Ridge preservation with applying PRGF, 2.Ridge preservation alone
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Main outcome variables
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Clinical parameters include vertical changes in dental apicoronal socket, degree of inflammation, trabecular thickness, bone-biomaterial contact, presence or absence of connective tissue in the reconstructed area, percentage of remnant particles, percentage of new bone formation, Number of blood vessels, bone vitality and foreign body reaction.