Protocol summary

Study aim
Effects of temporary clips on somatosensory evoked potentials in anterior circulation of brain aneurysm surgery
Design
The design of the study is a clinical trial with no control group and for 10 patients the intervention is done and blindness is not done.
Settings and conduct
In this research, all patients referred to the Hazrat Rasoul Akram hospital, who suffered from brain aneurysm will be enrolled. Effects of temporary clips on somatosensory evoked potentials in anterior circulation of brain aneurysm surgery will be investigated.
Participants/Inclusion and exclusion criteria
All patients referred to Rasoul Akram Hospital, who suffered from brain aneurysm, will be enrolled. Inclusion criteria: The patient's aneurysm is only related to the anterior circulation of the brain. Exclusion criteria: Patient with history of stroke, The patient with history of previous aneurysm surgery.
Intervention groups
The intervention is a temporary clips in anterior circulation of brain aneurysm surgery.
Main outcome variables
The amount of changes in brain electrical potential, The duration of blockage of the arteries with clips, Stroke

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20171124037606N2
Registration date: 2019-01-23, 1397/11/03
Registration timing: prospective

Last update: 2019-01-23, 1397/11/03
Update count: 0
Registration date
2019-01-23, 1397/11/03
Registrant information
Name
Alireza Tabibkhooei
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 6435 2228
Email address
tabibkhooei.a@iums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-02-04, 1397/11/15
Expected recruitment end date
2019-06-20, 1398/03/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effects of temporary clips on somatosensory evoked potentials in anterior circulation of brain aneurysm surgery
Public title
Effects of temporary somatosensory evoked potentials in brain aneurysm
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
The patient's aneurysm is only related to the anterior circulation of the brain
Exclusion criteria:
Patient with history of stroke The patient with history of previous brain aneurysm surgery
Age
No age limit
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 10
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Iran University of Medical Sciences
Street address
Iran University of Medical Sciences, Hemmat Highway, Tehran
City
Tehran
Province
Tehran
Postal code
1449614535
Approval date
2018-12-22, 1397/10/01
Ethics committee reference number
IR.IUMS.FMD.REC.1397.112

Health conditions studied

1

Description of health condition studied
Cerebral aneurysm
ICD-10 code
I67.1
ICD-10 code description
Cerebral aneurysm, nonruptured

Primary outcomes

1

Description
The amount of changes in brain electrical potential
Timepoint
Every 10 seconds
Method of measurement
With Somatosensory Evoked Potentials

2

Description
The duration of blockage of the arteries with clips
Timepoint
Continuously, from the time the clips is put up to remove it
Method of measurement
Based on patient records

3

Description
Stroke
Timepoint
During operation, after the completion of surgery, 3 days, 1 week and one month after surgery
Method of measurement
Based on patient records

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: temporary clips in anterior circulation of brain aneurysm surgery
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Hazrat Rasoul Akram hospital
Full name of responsible person
Alireza Tabibkhooei
Street address
Hazrate Rasool hospital, Niyayesh street, Sattarkhan
City
Tehran
Province
Tehran
Postal code
1445613131
Phone
+98 21 6435 2190
Email
hrmc@iums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Kazem Malakooti
Street address
Iran University of Medical Sciences, Hemmat Highway, Tehran
City
Tehran
Province
Tehran
Postal code
1445613131
Phone
+98 21 8670 2503
Email
research@iums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Iran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Asghar Aslani Nia
Position
Resident
Latest degree
Medical doctor
Other areas of specialty/work
Neurosurgery
Street address
Rasool Akram Hospital, Niayesh St. Sattarkhan St.
City
Tehran
Province
Tehran
Postal code
1354863411
Phone
+98 21 6688 2693
Email
dr.aslaninia@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Alireza Tabibkhooei
Position
Assistant Professor
Latest degree
Specialist
Other areas of specialty/work
Neurosurgery
Street address
Rasool Akram Hospital, Niayesh St. Sattarkhan St.
City
Tehran
Province
Tehran
Postal code
1445613131
Phone
+98 21 64351
Email
alireza.tabibkhooei@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Alireza Tabibkhooei
Position
Assistant Professor
Latest degree
Specialist
Other areas of specialty/work
Neurosurgery
Street address
Rasool Akram Hospital, Niayesh St. Sattarkhan St.
City
Tehran
Province
Tehran
Postal code
1445613131
Phone
+98 21 64351
Email
alireza.tabibkhooei@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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