The comparison of metoprolol and carvedilol in prevention of AF after CABGS

Comparison of the effect of cartidilol and metoprolol on the incidence of AF after cardiac surgery in patients undergoing open heart surgery in Imam Ali Hospital in 1997

To assign people to two groups, randomization is done by blocking method, which each intervention patient receives. As such, 6 blocks of 4 are provided as follows.1) AABB 2) ABAB 3) ABBA 4) BBAA 5) BABA 6) BAAB Block selection is based on the random number table. Group A patients receiving metoprolol and B patient receiving cartidilol.

In this study, double blind blindness is used so that the patient and the investigator who applies the interventions are not aware of the interventions. . After transferring patients to the department, monitoring of the 24-hourly electrocardiogram will be performed for five days

. The criteria for entering the study will be all patients who undergo cardiac surgery due to coronary artery disease or valvular abnormalities, preoperative beta-blocker therapy (propranol, metoprolol, cartidilol for heart rate of 60 to 70 Minutes) and obtaining written consent, patients with prior history of atrial fibrillation, receive class I, II antiarrhythmic drugs, digoxin, permanent or temporary pacemakers, each grade from the heart block, bradycardia with heart rate less than 50, end-stage renal disease (ESRD) ), Severe pulmonary disease (pneumonia, COPD) and severe liver disease (cirrhosis or hepatitis folinitis) They will not be included in the study.

In this randomized clinical trial, patients undergoing non-emergency open heart surgery candidates admitted to Ali ibn Abitaleb Zahedan Hospital will be divided into two groups of metoprolol, cartidilol to prevent the onset of AF.

AF incidence in patients after open heart surgery

To assign people to two groups, randomization is done by blocking method, which each intervention patient receives. As such, 6 blocks of 4 are provided as follows. 1) AABB 2) ABAB 3) ABBA 4) BBAA 5) BABA 6) BAAB Block selection is based on the random number table. Group A patients receiving metoprolol and B patient receiving cartidilol.

To assign people to two groups, randomization is done by blocking method, which each intervention is receiving. Patients and physicians are not aware of blind blindness. Block selection is based on the random number table. Group A patients receiving metoprolol and B patient receiving carveidilol.

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