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Study aim
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Determine the effect of combination changes of catheter size and negative suction pressure on hemodynamic and respiratory parameters in patients undergoing mechanical ventilation.
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Design
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Clinical trial without control group
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Settings and conduct
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Study will be done in the Shahid Beheshti and Imam Sajjad Hospitals in Yasuj. 1 minute before and after suction Oxygen will be 100% received and before connecting the catheter to the suction tube the negative suction pressure will be adjusted by blocking the end of the suction tube The suctioning catheter when struck, pull 1 cm back , suction will be performed 2 times for 10 seconds Between these ,the patient will be connected to the ventilator for 30 seconds
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: Minimum age of 18 and up to 65 years, connecting to a fixed volume ventilator , at least 24 hours before intervention in the intensive care unit Hospitalized and and has a size of 7.5 in the trachea tube , Stable hemodynamic status , Have a score of -2 to -5 based on the Richmond scale.
Exclusion criteria: Having respiratory illnesses like Asthma, emphysema, COPD and ARDS diagnosed by physician ,the use of positive inotropic drugs, such as dopamine and dobutamine 3- Severe cardiovascular and pulmonary failure , high intracranial pressure, score (-1 to 4+) based on Richmond's scale, blood coagulation disorder and thrombocytopenia
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Intervention groups
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35 patients in a single-group will be suctioned 4 times.initially with a catheter of 10 and a negative pressure of 100, second time a catheter of 10 and a negative pressure of 150 , third time a catheter of 12 and a negative pressure of 100 and fourth time the catheter size 12 and the negative pressure 150
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Main outcome variables
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Hemodynamic parameters and respiratory parameters will be recorded before, immediately, 10 and 20 minutes after suction.