The effect of boiled garlic and Shirazi lemon on blood lipids in hyperlipidemia patients
Design
Before and after clinical trial
Twenty-eight patients with hyperlipidemia in one group
Settings and conduct
This study will be conducted on patients with hyperlipidemia in Gonabad, Iran. The intervention includes 30 cc boiled garlic and lemon which will be taken by the patients in each meal for 3 weeks. Then, after one week wash-out period, the intervention will be repeated. Measuring blood lipids will be done before intervention, three weeks after the intervention, and at the end of the intervention.
Participants/Inclusion and exclusion criteria
Inclusion criteria:
1- Over 18 years old
2- with hyperlipidemia
3- Resident of Gonabad
4- Willing to participate in the study
Exclusion criteria:
1- Peptic ulcer
2- Indigestion
3- Gastrointestinal inflammatory diseases
4- Sensitivity to boiled garlic and lemon
5- Having Other chronic diseases
Intervention groups
Thirty cc boiled garlic and lemon will be taken by the patients in each meal for 3 weeks. Then, after one week wash-out period, the intervention will be repeated.
Main outcome variables
Cholesterol; triglyceride; LDL; HDL
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20190317043076N1
Registration date:2019-07-13, 1398/04/22
Registration timing:retrospective
Last update:2019-07-13, 1398/04/22
Update count:0
Registration date
2019-07-13, 1398/04/22
Registrant information
Name
Hosein َAjamzibad
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 51 5722 3028
Email address
ajam.h@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2014-04-04, 1393/01/15
Expected recruitment end date
2014-09-21, 1393/06/30
Actual recruitment start date
2014-04-21, 1393/02/01
Actual recruitment end date
2014-11-21, 1393/08/30
Trial completion date
2015-01-20, 1393/10/30
Scientific title
The effect of boiled garlic and Shirazi lemon on blood lipids in hyperlipidemic patients
Public title
The effect of boiled garlic and lemon on blood lipids
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Willing to participate in the study
Resident of Gonabad
Having hyperlipidemia
Over 18 years old
Exclusion criteria:
Peptic ulcer
Indigestion
Gastrointestinal inflammatory diseases
Sensitivity to boiled garlic and lemon
Having other chronic diseases
Age
From 18 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
28
Actual sample size reached:
28
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Gonabad University of Medical Sciences
Street address
Next to the Asian Road, Deputy for Research, Gonabad University of Medical Sciences, Gonabad, Iran
City
Gonabad
Province
Razavi Khorasan
Postal code
96917-93718
Approval date
2014-03-12, 1392/12/21
Ethics committee reference number
GMU.REC.1392.81
Health conditions studied
1
Description of health condition studied
Hyperglycemia
ICD-10 code
E78.2
ICD-10 code description
Mixed hyperlipidemia
Primary outcomes
1
Description
Level of blood cholesterol
Timepoint
Before intervention; three weeks after the intervention, and at the end of the intervention
Method of measurement
Autoanalyser: BT3000 PLUS
2
Description
Level of blood triglyceride
Timepoint
Before intervention; three weeks after the intervention, and at the end of the intervention
Method of measurement
Autoanalyser: BT3000 PLUS
3
Description
Level of blood LDL
Timepoint
Before intervention; three weeks after the intervention, and at the end of the intervention
Method of measurement
Autoanalyser: BT3000 PLUS
4
Description
Level of blood LDL
Timepoint
Before intervention; three weeks after the intervention, and at the end of the intervention
Method of measurement
Autoanalyser: BT3000 PLUS
Secondary outcomes
empty
Intervention groups
1
Description
Thirty cc boiled garlic and lemon will be taken by the patients in each meal for 3 weeks. Then, after one week wash-out period, the intervention will be repeated.