Comparison onset,duration and quality of axillary block with ropivacaine 0‎‏.‏‎5‎‏%‏‎ plus ‎dexmedetomidine and fentanyl‏ ‏and Verapamil in forearm surgeries ‎

Comparison onset,duration and quality of axillary block with ropivacaine 0‎‏.‏‎5‎‏%‏‎ plus ‎dexmedetomidine and fentanyl‏ ‏and Verapamil in forearm surgeries ‎

This study is clinical trial and double blind.105 patients candidate forearm surgery in Valiasr hospital will inter this study. We will divide patients in 3 groups by simple randomization. Groups are parallel.

This study is clinical trial and double blind.105 patients candidate forearm surgery in Valiasr hospital will inter this study. Outcome assessor and analyzer not aware from grouping. Codes of group are available to analyzer and outcome assessor.

Inclusion criteria:20 to 70 years, fracture of the forearm and hand, absence more than a fracture in the body or surgery, body mass index less than 35, not having blood coagulation and disorder PTT and PT and INR, lack of psychological problems, no pregnancy, absence of neurological disorders in the hand Exclusion criteria: Failure to cooperate with the patient to perform the block, allergy to drug, infection in block area, surgical time more than 150 minutes, block failure

First group: We inject 40 milliliter of Ropivacaine 0.5 % plus 1 micro gram in kilogram Dexmedetomidine. Second group:We inject 40 milliliter of Ropivacaine 0.5 % plus 1 micro gram in kilogram Fentanyl. Third group:We inject 40 milliliter of Ropivacaine 0.5 % plus 2.5 milligram Verapamil in kilogram Dexmedetomidine.

blood pressure, heart rate, oxygen saturation, pain, duration motor and sensory block, drug consumption

Simple individual randomization with random number table in division of groups in two groups A and B and C. Randomization method: Simple randomization. Random unit: Individual. How to build sequences: First, we set the framework for our statistical society. We started from a table point in a row or column. Given the type of code in the row, we chose the same number of digits. After that, the numbers control the path. We noticed smaller numbers of the statistical community. We have to continue this work so that the number of samples is completed.Even numbers were used for intervention group and odd numbers were used for the control group. Allocation concealment:Numbered drug containers

This study is double blind. Researcher who complete questionnaire and analyzer are blind (double blind).Outcome assessor and analyzer don't aware from grouping.The person evaluating the outcome is unaware of the grouping. Groups A and B and C are available to analyzer and outcome assessor.The syringe containing the drugs are covered and labeled as A and B and C at the discretion of anesthesiology residents.

When we publish article in journal

After the article is published

researcher in university

If there are additional questions

Dr Modir

They have to write letters to the professors and the university