Protocol summary

Study aim
Determining the effect of using an earplugs and eye mask on the quality of sleep, anxiety and delirium in patients hospitalized to the intensive care unit
Design
Two arm parallel group randomised trial with blinded care and outcome assessment
Settings and conduct
This study will be conducted in ICU in Qa'im and Imam Reza hospitals in Mashhad. All doctors and nurses in intensive care units will be aware of the research process and, for further certainty, a poster that summarizes the study process will be installed in any special section where it is appropriate and visible. In beginning of study and before sleep, baseline information from patients in both groups is collected by a group of researchers who are not aware of the type of study group (control and intervention). Nurses and patients will be asked to do not inform the researchers about the use or non-use of eye masks and earplugs in order to avoid the potential impact of their knowledge on the results of the study.
Participants/Inclusion and exclusion criteria
Orientation, GCS higher than 10, hospitalization to the intensive care unit for more than 72 hours, lack of any known cognitive impairment such as dementia, dizziness and delirium at the time of admission, lack of sleep disorders such as sleep apnea, narcolepsy, chronic insomnia and restless leg syndrome
Intervention groups
At 22 o'clock for 3 nights, the nurse will be reminded to use an ear tag and eye mask for the intervention group and at 6 o'clock in the morning to help the patient remove it and, where appropriate, in the wardrobe of the patient and out of the view. The control group will not use the same nights before a specific device.
Main outcome variables
quality of sleep, anxiety and delirium

General information

Reason for update
Acronym
ICU
IRCT registration information
IRCT registration number: IRCT20190407043189N1
Registration date: 2019-05-25, 1398/03/04
Registration timing: retrospective

Last update: 2019-05-25, 1398/03/04
Update count: 0
Registration date
2019-05-25, 1398/03/04
Registrant information
Name
Mahnaz Bahrami
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 56 3238 1443
Email address
bahramim@bums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2014-11-22, 1393/09/01
Expected recruitment end date
2015-03-20, 1393/12/29
Actual recruitment start date
2015-01-21, 1393/11/01
Actual recruitment end date
2015-06-20, 1394/03/30
Trial completion date
2015-06-23, 1394/04/02
Scientific title
The effect of using earplugs and eye masks during night on sleep quality, anxiety and onset of delirium in hospitalized patients in ICU at Imam Reza and Qaem hospitals in Mashhad
Public title
The effect of earplugs and eye masks on sleep quality, anxiety and onset of delirium in hospitalized patients in ICU
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria:
Patient has Orientation GCS higher than 10 The patient is hospitalized to the intensive care unit for more than 72 hours The patient has the ability to put an earplugs and eye mask independently
Exclusion criteria:
The patient has any known hearing impairment The patient will have any known cognitive impairment such as dementia, dizziness and delirium at the time of admission The patient has any sleep disturbances such as sleep apnea, narcolepsy, chronic insomnia and restless leg syndrome at the start of the study The patient has an addiction to any drug The patient has a history of night work during the past 3 years
Age
From 18 years old to 75 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 40
Actual sample size reached: 37
Randomization (investigator's opinion)
Randomized
Randomization description
Random assignments will be made using the production of random online numbers on the relevant websites. Before the study, the researchers agreed that the first time random numbers were assigned to the control group and the second time to the intervention group. At first, the range of numbers is from 1 to 80, and then 40 random numbers for the control group and again 40 random numbers for the intervention group will be selected.The option "Not repeat numbers" will also be considered. Then the qualified patients will be numbered and will be numbered in control and intervention groups based on their number.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Mashhad University of Medical Sciences
Street address
Nursing & Midwifery school, Ebn-sina Ave., Doctora Crossroad., Daneshgah Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
9137913199
Approval date
2014-11-16, 1393/08/25
Ethics committee reference number
910587

Health conditions studied

1

Description of health condition studied
Delirium
ICD-10 code
ICD-10 code description
F05

Primary outcomes

1

Description
quality of sleep
Timepoint
Night 1, 2 and 3 Use earplugs and eye mask
Method of measurement
Voran-Schneider-Halper's quality of sleep questionnaire

2

Description
Anexiety
Timepoint
Night 1, 2 and 3 Use earplugs and eye mask
Method of measurement
Hospital anxiety and depression questionnaire

3

Description
Delirium
Timepoint
Night 1, 2 and 3 Use earplugs and eye mask
Method of measurement
NEECHAM Confusion Scale

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: The nurse will put an earplugs and eye mask on the patient at 22 o'clock and leave at 6 o'clock in the morning and put in the patient's closet. This is done for 3 consecutive nights.
Category
Prevention

2

Description
Control group: In the control group no special equipment will be used during the night.
Category
N/A

Recruitment centers

1

Recruitment center
Name of recruitment center
Ghaem hospital
Full name of responsible person
Simin Sharafi
Street address
Ghaem Hospital., Ahmad abad Blv., Dr. Ali Shariati Square.
City
Mashhad
Province
Razavi Khorasan
Postal code
91766-99199
Phone
+98 51 3840 0000
Email
Quaem.Medical.Center@mums.ac.ir

2

Recruitment center
Name of recruitment center
Imam Raza hospital
Full name of responsible person
Simin Sharafi
Street address
Imam Reza hospital., Imam Reza Square., Ebn-Sina Ave., Doctora Crossroad., Daneshgah Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
9137913316
Phone
+98 51 3854 3031
Email
emamreza@mums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Robab Latif Nejad Roodsari
Street address
Nursig & Midwifery school., Ebn-sina Ave., Doctora Squre., Daneshgah Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
9137913199
Phone
+98 51 3859 1511
Email
nms.it@mums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Mashhad University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Fatemeh Hajiabadi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Nursing @ Midwifery school., Ebn-sina Ave., Doctora Squre., Daneshgah Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
9137913199
Phone
+98 51 3859 1511
Email
HajiabadiF@mums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Fatemeh Hajiabadi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Nursing & Midwifery school., Ebn-sina Ave., Docrora Squre., Daneshgah Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
9137913199
Phone
+98 51 3859 1511
Email
hajiabadif@mums.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Birjand University of Medical Sciences
Full name of responsible person
Mahnaz Bahrami
Position
Instractor
Latest degree
Master
Other areas of specialty/work
Nursery
Street address
Birjand University of Medical Siences., Ayat-Allah Ghafari Blv.
City
Birjand
Province
South Khorasan
Postal code
9717853577
Phone
+98 56 3239 5000
Email
bahramim@bums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
The original outcome information will be shared.
When the data will become available and for how long
Start the access period 6 months after printing the results
To whom data/document is available
Data will be available to researchers working in academia.
Under which criteria data/document could be used
-
From where data/document is obtainable
siminsharafi68@gmail.com
What processes are involved for a request to access data/document
Send an email to siminsharafi68@gmail.com and respond within 10 business days
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