The purpose of this study was to evaluate the effects of a "Home Base Exercise" plan on metabolic and hormonal parameters in patients with PCOs. Forty PCO patients of Gynecologic or Endocrinologic clinic were assigned to intervention or control group based on a block randomization method. A "Home Base Exercise" plan including 30 minutes of aerobic and resistive exercises 3 times a week was given to patients in the intervention group; and no exercise program to the control group. In both group, the routine treatments (according to Gynecologic or Endocrinologic clinic) and regular diet were continued and they were followed for 3 months. Age, Weight, Body Mass Index (BMI), Blood Pressure, Abdominal Circumference and Abdominal: gluteal circumference ratio was measured at the beginning of the study. Serum concentration of TSH, Prolactin, 17-Hydroxy Progestrone (17-OHP), Testosterone, FBS, Insulin, TG, Cholesterol, HDLc, and hsCRP were measured at the beginning of the study and at the end of the 3 month period of exercise program.