Evaluation the effect of dexmedetomidine with bupivacaine and bupivacaine alone on postoperative pain in upper limb ortopedice surgery with supraclavicular block

The purpose of this study will be to assess the effect of dexmedetomidine with bupivacaine and bupivacaine alone on postoperative pain in upper limb ortopedice surgery with supraclavicular block

Clinical trial with two arm parallel groups, randomised trial with double blinded assessment. Study phase will be 3-2.

In Urmia Imam Khomeini hospital operating room after the onset time of the sensory and motor block, the duration of the sensory and motor block and postoperative pain will be measured.

inclusion criteria: aged 20-60 years old; American Society of Anesthesiologists physical status classification I; general anesthesia. Exclusion criteria: history of cardiovascular disease; history of respiratory disease; history of renal disease; history of liver disease; pregnancy; allergy to the drugs studied; contraindication of supraclavicular block; coagulopathy.

In Intervention group patients will be received 39 ml of bupivacaine 0.25% with 1 ml (1 µg/kg) dexmedetomidine. In control group patients will be received 39 ml of bupivacaine 0.25% with 1 ml saline 0.9%.

Duration of the sensory and motor block; post operative pain

Correction of the date of illness getting patient

Patients will be randomly assigned into two groups of Dexmedetomidine and Bupivacaine (group D) and Bupivacaine (group B) using Random Allocation Software 2.0, and the target codes will be written and placed in sealed envelopes with sequential allocation using double-blind method.

The anesthesiologist will be unaware of which patient will be assigned to which group. Syringes will be identical and only the operating room nurse will knew about the contents of each of them, and finally, after collecting information from the anesthesia residents, the anesthesiologist will be informed of the group each patient will be assigned to.