Protocol summary

Study aim
Evaluation of Neuropsychological Interventions on visual function in low vision children: A single arm clinical trial
Design
The single arm clinical trial was conducted with a 5-person group of visually impaired children. The method has the following three features: 1. Repeated measurements during a trial of the dependent variable. 2. Run multiple test situations for each participant (for example, each person is in both the trial (intervention) and baseline (control) positions. 3. Each participant is considered as a basis for comparing effectiveness of experimental situation. The reason for choosing such a plan is that each person can be in both a control and an intervention position, while being repeatedly measured in each position to ensure consistency in the individual's score and readiness to move to the next position.
Settings and conduct
The single arm clinical trial applied on 5 children with low vision in dark room of Tavakol rehabilitation center. All 5 low vision children were initially given 4 sessions in baseline (control), then 8 sessions in experimental (intervention) and 4 sessions in baseline (control) again, at the end of each session was measured their visual function.
Participants/Inclusion and exclusion criteria
1. age : 4 between 6 2. exclude other sensitive defect 3.exclude autism 4. exclude ADHD
Intervention groups
Intervention involves training and rehabilitation on a group of 5 visually impaired children by applying rehabilitation exercises implemented on the optical stimulus system.
Main outcome variables
Upgrading the subjects in the following variables: 1. Light Detection 2. Color Perception 3. Color Recognition 4. Shape Recognition 5. Shape Recognition from background 6. Detail Recognition 7. Visual Tracking 8. Visual Memory and sequence of Visual Memory 9. Eye-hand coordination 10. Depth Detection

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20190620043955N1
Registration date: 2019-12-08, 1398/09/17
Registration timing: retrospective

Last update: 2019-12-08, 1398/09/17
Update count: 0
Registration date
2019-12-08, 1398/09/17
Registrant information
Name
Elaheh Moazeni
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 31 3230 0141
Email address
moazeni.bme@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-01-20, 1397/10/30
Expected recruitment end date
2019-02-18, 1397/11/29
Actual recruitment start date
2019-01-20, 1397/10/30
Actual recruitment end date
2019-02-18, 1397/11/29
Trial completion date
2019-03-19, 1397/12/28
Scientific title
Neuropsychological Interventions on low vision children
Public title
The effect of educational and visual rehabilitation exercises on the visual function of low vision children
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Having a defect in eyesight- Being visually impaired Having aged 4-6 years
Exclusion criteria:
Lack of ADHD Lack of Autism Lack of defect in other senses
Age
From 4 years old to 6 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 5
Actual sample size reached: 5
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Isfahan University of Medical Sciences
Street address
Hezar Jerib street, Isfahan, Iran
City
isfahan
Province
Isfehan
Postal code
8174673461
Approval date
2018-03-03, 1396/12/12
Ethics committee reference number
IR.MUI.REC.1396.3.961

Health conditions studied

1

Description of health condition studied
Low vision
ICD-10 code
H54.2
ICD-10 code description
Low vision, both eyes

Primary outcomes

1

Description
1. Light Detection
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

2

Description
2. Color Perception
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

3

Description
3. Color Recognition
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

4

Description
4. Shape Recognition
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

5

Description
5. Shape Recognition from background
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

6

Description
6. Detail Recognition
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

7

Description
7. Visual Tracking
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

8

Description
8. Visual Memory and sequence of Visual Memory
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

9

Description
9. Eye-hand coordination
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

10

Description
10. Depth Detection
Timepoint
Total number of sessions: 16, 4 session per week, 1 houre for every session (4 sessions before intervention, 8 sessions intervention and 4 sessions after intervention)
Method of measurement
complete case report form based on Likert scale

Secondary outcomes

empty

Intervention groups

1

Description
Intervention involves training and rehabilitation on a group of 5 visually impaired children by applying rehabilitation exercises implemented on the optical stimulus system. The clinical trial applied in dark room of Tavakol rehabilitation center. All 5 low vision children were initially given 4 sessions in baseline (control), then 8 sessions in experimental (intervention) and 4 sessions in baseline (control) again, at the end of each session was measured their visual function.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Tavakol Rehabilitation Center of Family and Low Vision and Blindness Children
Full name of responsible person
Fateme Tavakolli
Street address
No. 27, 22 Bahman Alley, Falatory Ave, Isfahan, Iran
City
isfahan
Province
Isfehan
Postal code
8174673461
Phone
+98 31 3568 6202
Email
markazetavakol@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice-Chancellery for Research and Technology of Isfahan University of Medical Sciences
Full name of responsible person
Dr.ShaghayeghHaghjoo Javanmard
Street address
Hezar Jerib street, Isfahan
City
Isfahan
Province
Isfehan
Postal code
73461-81746
Phone
+98 31 3792 3071
Email
research@mui.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice-Chancellery for Research and Technology of Isfahan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Dr. Saeed Kermani
Position
Associate Professor
Latest degree
Ph.D.
Other areas of specialty/work
Medical Engineering
Street address
Hezar Jerib street, Isfahan, Iran
City
Isfahan
Province
Isfehan
Postal code
8174673461
Phone
+98 31 3792 3861
Email
kermani@med.mui.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Dr. Saeed Kermani
Position
Associate Professor
Latest degree
Ph.D.
Other areas of specialty/work
Medical Engineering
Street address
Hezar Jerib street, Isfahan, Iran
City
Isfahan
Province
Isfehan
Postal code
8174673461
Phone
+98 31 3792 3861
Email
kermani@med.mui.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Esfahan University of Medical Sciences
Full name of responsible person
Dr. Saeed Kermani
Position
Associate Professor
Latest degree
Ph.D.
Other areas of specialty/work
Medical Engineering
Street address
Hezar Jerib street, Isfahan, Iran
City
Isfahan
Province
Isfehan
Postal code
8174673461
Phone
+98 31 3792 3861
Email
kermani@med.mui.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Undecided - It is not yet known if there will be a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Undecided - It is not yet known if there will be a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Undecided - It is not yet known if there will be a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
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