Parturient patients (72 patients) are admitted to fatemieh hospital of hamedan candidate for elective cesarean section in 1389, are described about procedure and after signation of consent forms,if they have not excluded criteria, divided to two groups of treatment and control in accidence (random block).
The study is double blind and non of patients and nurses aware of administered drugs( The syringes of dugs are coded). In treatment group, 15 minutes before spinal anesthesia, 1.5 mg/kg of bolous lidocaine 2% is injected intravenously. Then patients are spinal anesthetized with 12.5 mg. marcaine 0.5% and 2.5 micrograms of sterile sufentanil with spinal needle No.25 .After prep and drape and in time of beginning of skin incision by surgeon, infusion of maintenance drug is initiated in treatment group,1.5mg./kg./h iv lidocaine 2%. Infusion of drug continue half past end of surgery in recovery unit. After then,drug is discontinued.In control group,we use normal salin intravenously instead of lidocaine.The volume of normal salin is the same of lidocaine, based on milliliter( 15 min. before spinal anesthesia , bolous dose of normal salin is injected, Then patients are anesthetized spinaly with 12.5 mg. marcaine 0.5% and 2.5 micrograms of sterile sufentanil with spinal needle No.25 ,and just in time of skin incision, maintenance dose of normal salin is iniciated until half past end of surgey,in recovery unit). During study, the patients are monitored completely and vital signs are recorded. The severity of pain is recorded in 15 min. before spinal anesthesia, just before spinal anesthesia, 5 min. later, and then, 10 min., 15 min. ,30 min., 1hour, 2, 4, 6, 12, 24 hours after that by V.A.S.(visual analog scale) criteria. This criteria is used for assessment of severity of pain and has 0 to 10 scores. The patient asked for this score . all scores recorded. 0 score means completely without pain and 10 score means terrible pain. An upper score reveals more pain. if the patient suffer from pain during this study, with scores above 4,analgesic drugs are used. If the score. is 4-6 , supp. Diclofenac Na. 100mg. are administered and if the score is 7-10 , intravenous morphin sulfate are used. The name and rate of analgesic drugs are recorded. The main goal of this study is whether iv lidocaine in contrast with placebo could has analgesic effects on spinal anesthetized cesarean section patients.