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Study aim
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Evaluation of response to treatment and comparison of normal saline and hypertonic saline nebulizer in the bronchiolitis
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Design
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The design of the study is a randomized clinical trial. The randomization method is blocked. The sample size for each study group is 60.
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Settings and conduct
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All patients referred to the Ali Asghar Hospital, who suffered from bronchiolitis will be enrolled. Patients will be randomly divided into two groups based on 10 blocks. A total of 60 patients will be examined. Patients and data analyzer will be blind.
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Participants/Inclusion and exclusion criteria
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All patients referred to the Ali Asghar Hospital, who suffered from bronchiolitis will be enrolled. Inclusion criteria: patients over 1year, Clinical evidence of respiratory viral infection, Body temperature 38 degrees Celsius and above, Abnormal breathing rate based on age range, High heart rate due to age range, coryza. Exclusion criteria: Patients over 10 years old, History of more than two episodes of respiratory distress in the past, Chronic heart and pulmonary disease, Safety defect, Down syndrome, Metabolic or neurological disease
Use of mechanical ventilation in neonatal period, Positive family history of asthma, Sick patient requiring immediate hospitalization due to dehydration, decreased consciousness, lethargy, or respiratory failure symptoms
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Intervention groups
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In control group Patients will receive 3 ml normal saline 0.9% each 20 minutes for 3 times and 8 liters of oxygen per minute via nebulizer.
In intervention group Patients will receive 3 ml of hypertonic saline 3%, each 20 minutes for 3 times and 8 liters of oxygen per minute via nebulizer.
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Main outcome variables
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The number of pulses,The number of pulses, Breath rate