Inclusion criteria:
Patients with Polycystic ovary Syndrome based on two criteria of the three diagnostic criteria of the disease based on Rotterdam: 1.Bleeding is reduced or discontinued (as Delay more than 35 days or less than 8 bleeding episodes per year) 2. Clinical symptoms including hirsutism or Ferriman-Gallway (MGF) score above 8, acne and male pattern baldness and biochemical symptoms of increased androgenesis. 3. Polycystic ovary (12 or more of 12 follicles per ovary with a diameter of 2 to 9 mm, or an increase in ovarian volume to more than 310 ml). Patients with age between 20 to 40 years old.
patient's acceptance of taking part in the study.
Exclusion criteria:
Those who take drugs of anticoagulants and hyperlipidemia
Use Tobacco
Having kidney disease, diabetes, liver disease, cardiovascular disorders, hypothyroidism, inflammatory and rheumatic diseases, hyperprolactinemia, Cushing's syndrome, and congenital adrenal hyperplasia Follow a particular diet in the last three months.
Take medications that affect insulin sensitivity, inflammation, or lipid profile and hormonal profile, including glucocorticoid drugs, ovulation induction drugs, anti-obesity, anti-diabetes, antihypertensive, estrogenic, anti-androgen, over the past 3 months
Unwilling to participate in the study
Use of Nutrition Supplements in the last 2 months
Pregnancy or breastfeeding
Sensitization or allergy to sumac