The effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes and fasting blood sugar in patients with metabolic syndrome

Effect of vitamin B1 (thiamine) on blood pressure, lipid profile, liver enzymes, fasting blood sugar, metabolic syndrome patients in military patients referred to 525(khorramabad) Army Hospital

This study was performed as randomized, parallel controlled clinical trial on 116 patients with Mets

This study was performed as randomized, parallel controlled clinical trial on 116 patients with Metabolic Syndrome. In this study, while receiving written informed consent from patients, participants were blinded to receiving drugs and placebo.

Age range for the present study 25 to 50 years is considered and accordingly, subjects that aged 25- 50 years, and according to IDF criteria, waist circumference shall be equal to or greater than 94 and 80 cm in men and women, respectively. In addition to waist circumference, if candidates meet two of the following 4 criteria, they will be diagnosed with MetS: Fasting blood sugar above 100 mg / dl  Triglycerides equal to or greater than 150 mg / dL  Blood pressure equal to or greater than 135/85 mm Hg   HDL less than 40 and 50 mg / dl in men and women, respectively No admitance and exclusion criteria from study History of cardiovascular disease Hepatic, renal and metabolic disorders Alcohol , cigarettes, supplements and certain drugs consumption People who during the study less than 80% of the tablets vitamin b1 (thiamin) and placebo to consume

Participants into two categories consumer vitamin b1 and placebo divided

Indicators of profail lipidi(TG-Chol-HDL-LDL) , liver enzymes(ALT- AST), fasting blood suger, blood perser systolic ,blood perser diystolic

A simple dice randomization method was used in which paired numbers for the intervention group and individual numbers for the control group were used.

Intervention and randomization were performed through a random allocation list by a member of the research team as the only blinded individual to the assignment. Other members of the research team (including team leader and study coordinator), as well as all participants, were randomly assigned to groups and intervention and remained blind until the end of the study.

Because of the confidentiality of the information on the civilians