The effect of curcumin supplementation on lipid profile, liver enzymes, inflammatory factors and hepatic steatosis in patients with Nonalcoholic Fatty Liver Disease

Inclusion criteria:

Age >18 years old Controlled Attenuation Parameter (CAP score)>263 Having a history of alcohol consumption less than 10 mg per day in women and less than 20 mg per day in men Absence of other acute and chronic diseases and disorders of the liver (hepatitis B, C, etc.), biliary disease, known autoimmune diseases, cancer and inherited disorders affecting liver condition (storage disease of iron, and copper. ..) Absence of Hypertension, cardio - vascular diseases, lung disease and kidney disease, cirrhosis and celiac disease Absence of pregnancy or lactation Athletes or hospitalization Not consume medications such as metformin, vitamin E and Ursodeoxycholic Acid (UDCA) Not consume hepatotoxic drugs such as phenytoin, tamoxifen and lithium and corticosteroids and methotrexate Not consume medications of antibiotics over a week during the study period or before entering it No history of weight loss surgery in the past year the 3-month weight loss program No history of hypothyroidism, Cushing's syndrome and diabetes Lack of gall bladder disease

Exclusion criteria:

Target sample size: 50