The purpose of this study will be determination of the acute effect of circuit exercise on hematological indices and blood hepcidin before and after twelve weeks of compound set training in active men
Design
Twenty healthy resistance trained men will be randomly divided into two 10 people in experimental and control groups
Settings and conduct
The exercises and blood sampling are done in the gym by an experienced trainer and by the nurse respectively.Subjects perform a circular training session before and after 12 weeks of resistance compound set training and blood sampling is taken before and after this one session.
Participants/Inclusion and exclusion criteria
Subjects are resistance trained men who have no cardiovascular and musculoskeletal diseases
Intervention groups
The experimental group will perform a circular exercise session. 48 hours after this session, the 12-week training period begins and ends. They then repeat the circular exercise.
The control group will perform the same circular exercise before and after 12 weeks as the experimental group but with no exercise in these 12 weeks.
Main outcome variables
Hepcidin; Fe; Ferritin; red blood cells; white blood cells; Platelet; hemoglobin
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20190927044893N1
Registration date:2020-03-22, 1399/01/03
Registration timing:retrospective
Last update:2020-03-22, 1399/01/03
Update count:0
Registration date
2020-03-22, 1399/01/03
Registrant information
Name
Roghayyeh Afroundeh
Name of organization / entity
University of Mohaghegh Ardabili
Country
Iran (Islamic Republic of)
Phone
+98 45 3359 3278
Email address
afroundeh@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-08-23, 1398/06/01
Expected recruitment end date
2019-11-21, 1398/08/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Acute effect of circuit training on blood hematological factors and Hepcidin before and after 12 weeks compound set training in active male
Public title
Effect of one session and a period of resistance training on blood hematological factors
Purpose
Basic scienece
Inclusion/Exclusion criteria
Inclusion criteria:
resistance trained male
Exclusion criteria:
having any musculoskeletal injuries
using any drugs or supplements
Levels of blood variables such as iron, ferritin and hepcidin in abnormal range
Age
From 20 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
20
Randomization (investigator's opinion)
Randomized
Randomization description
The random number table will be used for simple randomization to assign subjects to the group. To use Random Number Tables, the researcher must first determine direction for reading numbers in table (for example, up, down, left or right).The second step for researcher is considering numbers for different groups (eg, even numbers for intervention A and odd numbers for intervention B).The researcher then selects one number and moves in one of the predetermined directions, records the numbers and assigning them to different groups.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Ardabil University of Medical Sciences
Street address
Ardabil, University of Mohaghegh Ardabili, Department of sport science
City
Ardabil
Province
Ardabil
Postal code
5619911367
Approval date
2019-07-21, 1398/04/30
Ethics committee reference number
IR.ARUMS.REC.1398.197
Health conditions studied
1
Description of health condition studied
iron metabolism in athletes
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Hepcidin
Timepoint
pre and post of the circular exercise before the 12 weeks of compounding exercise and again pre and post of the circular exercise after completing the 12 weeks of compounding exercise
Method of measurement
Hepcidin by Elisa reader
2
Description
Fe
Timepoint
pre and post of the circular exercise before the 12 weeks of compounding exercise and again pre and post of the circular exercise after completing the 12 weeks of compounding exercise
Method of measurement
Fe by auto analyzer
3
Description
Ferritin
Timepoint
pre and post of the circular exercise before the 12 weeks of compounding exercise and again pre and post of the circular exercise after completing the 12 weeks of compounding exercise
Method of measurement
Ferritin by Gama counter
4
Description
Blood cells count
Timepoint
pre and post of the circular exercise before the 12 weeks of compounding exercise and again pre and post of the circular exercise after completing the 12 weeks of compounding exercise
Method of measurement
Automated cell counter
5
Description
Hemoglobin
Timepoint
pre and post of the circular exercise before the 12 weeks of compounding exercise and again pre and post of the circular exercise after completing the 12 weeks of compounding exercise
Method of measurement
Auto cell counter
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group: Subjects in this group will perform one circuit training session consisting of 10 resistance training stations with 40 to 60% of one maximal repetition. Then they will participate in a 12 weeks of resistance compound set training protocol. After this period, they will repeat a circuit training session.
Category
Diagnosis
2
Description
Control group: Subjects in this group will perform one circuit training session consisting of 10 resistance training stations with 40 to 60% of one maximal repetition. they will not participate in any activity during 12 weeks and after this period they will repeat a circuit training session.
Category
Diagnosis
Recruitment centers
1
Recruitment center
Name of recruitment center
University of Mohaghegh Ardabili
Full name of responsible person
Roghayyeh Afroundeh
Street address
Department of Physical Education and Sport sciences, University of Mohaghegh Ardabili, Ardabil
City
Ardabil
Province
Ardabil
Postal code
5619956131
Phone
+98 45 3359 3278
Email
afroundeh@gmail.com
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
University of Mohaghegh Ardabili
Full name of responsible person
Roghayyeh Afroundeh
Street address
Department of Physical Education and Sport Sciences, University of Mohaghegh Ardabili, Ardabil
City
Ardabil
Province
Ardabil
Postal code
5619911367
Phone
+98 45 3359 3278
Email
afroundeh@gmail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
University of Mohaghegh Ardabili
Proportion provided by this source
50
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic
Person responsible for general inquiries
Contact
Name of organization / entity
University of Mohaghegh Ardabili
Full name of responsible person
Roghayyeh Afroundeh
Position
Faculty member
Latest degree
Ph.D.
Other areas of specialty/work
exercise physiology
Street address
Ardabil, University of Mohaghegh Ardabili, Department of Sport science
City
Ardabil
Province
Ardabil
Postal code
5619911367
Phone
+98 45 3359 3278
Email
afroundeh@gmail.com
Person responsible for scientific inquiries
Contact
Name of organization / entity
University of Mohaghegh Ardabili
Full name of responsible person
Roghayyeh Afroundeh
Position
Faculty Member
Latest degree
Ph.D.
Other areas of specialty/work
Exercise Physiology
Street address
Department of Physical Education and Sport Sciences, University of Mohaghegh Ardabili, Ardabil
City
Ardabil
Province
Ardabil
Postal code
5619911367
Phone
+98 45 3359 3278
Email
afroundeh@gmail.com
Person responsible for updating data
Contact
Name of organization / entity
University of Mohaghegh Ardabili
Full name of responsible person
Roghayyeh Afroundeh
Position
Faculty Member
Latest degree
Ph.D.
Other areas of specialty/work
Exercise Physiology
Street address
Department of Physical Education and Sport Sciences, University of Mohaghegh Ardabili, Ardabil
City
Ardabil
Province
Ardabil
Postal code
5619911367
Phone
+98 45 3359 3278
Email
afroundeh@gmail.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
No - There is not a plan to make this available
Title and more details about the data/document
There is possibility to share results and statistical information
When the data will become available and for how long