Efficacy of flax seed oil in treating mild to moderate psoriasis vulgaris comparing with topical Bethamethasone: A randomized, double-blind, clinical trial

Evaluation of the effect of flaxseed on the treatment of skin lesions with mild to moderate severity of psoriasis vulgaris compared with topical betamethasone ointment.

A double-blind randomized clinical trial on 50 patients

- Among the clients of the dermatological clinic for Tehran Hazrat-e-Rasool Akram Hospital, 50 patients with psoriasis vulgaris, having the survey inclusion criteria, will be selected (by a plan executor physician) and included in the survey, giving some verbal comments to them and taking their written consent forms. At the beginning of the study, a questionnaire for individual information, and also two PASE and life quality questionnaires will be filled out by the researcher, observing the lesions and inquiring the patient. Then, the patients will be divided into two groups randomly, based on the table of random numbers; one group will apply Betamethasone product, and the second group will apply flax seed oil ointment on the lesions locally twice a day for 4 weeks. At the end of 4th week, the patients will be evaluated again by the therapist and researcher, based on both questionnaires, observing the lesions, and also the questions of the questionnaires. Moreover, both groups will be inquired about their satisfaction with treatment, according to scoring

- All patients between 18-60 years old, suffering psoriasis vulgaris plaque type with mild to moderate signs, not with intensifying psoriasis disease, and not to take medicines affecting psoriasis

- In the control group, Betamethasone ointment is applied twice a day, and in the intervention group, the ointment of flax seed oil is applied locally twice a day for 4 weeks..

Redness, Degree of Thickness, Degree of Scaling, Extent of Scrap, Quality of Life, Passive Intensity

A random number is allotted the patients, through the table of random numbers; a sealed envelope is delivered to him, and a random code is allocated to his medicine box. Data analysis is performed by the statistical software.

- The participants will receive a code, based on the table of random numbers; then, according to the code, they will receive one of the containers containing the product or Betamethasone. Both medicines are in the same containers with a uniform shape and color, and the patient will receive a treatment container and medicine, merely based on the code, inserted on the treatment box. This code will be repeated by the end of the study, neither the clinical observer nor the patient will be aware of the received medicine type, and only the container code will be given to them.