Protocol summary

Study aim
Determination of the effect of vibration on pain intensity during heel blood sampling in neonates
Design
The study will be a clinical trial with a parallel control group without blinding. In this study, 94 infants will be selected by sequential method and randomly divided into control and intervention groups with 4 blocks sampling
Settings and conduct
The research setting will be the neonatal intensive care unit of Rasoul Akraml and intervention will be performed on the third day of hospitalization during screening tests
Participants/Inclusion and exclusion criteria
Neonates with a gestational age of 47-37 weeks, weighing between 2500 and 4000 g without heart, respiratory and neurological problems and without physical and chromosomal abnormalities were included in this study.
Intervention groups
1- Assessment of pain before intervention in experimental and control groups. 1- produce vibration by placing mechanical vibrator, approximately 30 seconds before the heel stick, the vibrator will be applied over the mid/lateral calf, just below the knee for 30-second in in intervention group. 3- Re- assessment pain during heel blood sampling and 2 minutes after that in experimental and control groups.
Main outcome variables
Reduce pain during blood sampling by lancet the baby's foot

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20160119026104N10
Registration date: 2020-01-27, 1398/11/07
Registration timing: registered_while_recruiting

Last update: 2020-01-27, 1398/11/07
Update count: 0
Registration date
2020-01-27, 1398/11/07
Registrant information
Name
Mahnaz Shoghi
Name of organization / entity
Iran university of medical sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 4687 1192
Email address
shoghi.m@iums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-12-22, 1398/10/01
Expected recruitment end date
2020-05-21, 1399/03/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of vibration on pain Intensity of Heel-Blood Sampling in Neonates
Public title
Effect of vibration on pain Intensity
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria:
Birth weight between 2500 to 4000 g No analgesics or sedatives or anticonvulsants during the 12 hours prior to blood sampling No experience of painful procedure 24 hours before the intervention
Exclusion criteria:
Heart, respiratory and neurologic problems or any chromosomal and anatomical abnormalities
Age
From 256 days old to 294 days old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 47
Randomization (investigator's opinion)
Randomized
Randomization description
Random allocation blocks of two groups with four blocks
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Iran University of Medical Sciences
Street address
Tehran, Valiasr Ave., higher than Vanak Square, Rashidiassemi Avenue, Iran Nursing Midwifery Faculty
City
Tehran
Province
Tehran
Postal code
1996713883
Approval date
2018-09-28, 1397/07/06
Ethics committee reference number
IR.IUMS.REC.1397.510

Health conditions studied

1

Description of health condition studied
Pain
ICD-10 code
ICD-10 code description

Primary outcomes

1

Description
Pain
Timepoint
Pain measurement before intervention, Pain measurement during heel blood sampling, Pain measurement 2 minutes after heel blood sampling
Method of measurement
Premature Infant Pain Profile (PIPP)

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Use a mini vibrator(Norco MiniVibrator North Coast Medical Inc,NC70209, Gilroy, California) operates at 92 Hz and an amplitude of 0.6 mm) . to produce Vibration by placing the vibrator for 5 seconds before taking blood sampling from the baby's heel, in place of over the mid/lateral calf, just below the knee in accordance with the sural dermatome)
Category
Other

2

Description
Control group: Assessment of pain before, during and 2 minutes after taking blood sampling from infant's heel.
Category
N/A

Recruitment centers

1

Recruitment center
Name of recruitment center
Rasoul Akram Hospital
Full name of responsible person
Ms. Azam Abbasi
Street address
Sattar Khan Street. Niyayesh Street. Rasoul-e-Akram
City
Tehran
Province
Tehran
Postal code
۱۴۴۵۶۱۳۱۳۱
Phone
+98 21 6651 5000
Fax
+98 21 6651 5000
Email
abasi.azam@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Dr. Seid Kazam Malakuti
Street address
School of Nursing and Midwifery, Shahid Yasemi Street., North Kordestan Highway., Tehran., IRAN
City
Tehran
Province
Tehran
Postal code
1996713883
Phone
+98 21 4365 1000
Email
PR@iums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Iran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Mahnaz Shoghi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Tehran, Valiasr Ave, above Vanak Square, Rashid Yasemi Ave., Iran Nursing Midwifery Faculty
City
Tehran
Province
Tehran
Postal code
1996713883
Phone
+98 21 4365 1000
Email
shoghi.m@iums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Mahnaz Shoghi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Nursing and Midwifery School, Shahid Yasemi Street., North Kordestan Highway., Tehran., Iran
City
Tehran
Province
Tehran
Postal code
1996713883
Phone
+98 21 4365 1000
Email
shoghi.m@iums.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Mahnaz Shoghi
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Nursery
Street address
Nursing and Midwifery School, Shahid Yasemi Street., North Kordestan Highway., Tehran., Iran
City
Tehran
Province
Tehran
Postal code
1996713883
Phone
+98 21 4365 1000
Email
shoghi.m@iums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
After Data coding in order to keep the confidentiality of the participants in the research.
When the data will become available and for how long
The end of sampling till six months after article publishing.
To whom data/document is available
Ethical, Reviewer and Editorial committees, Researchers.
Under which criteria data/document could be used
Systematic review and meta-analysis or secondary analysis citation
From where data/document is obtainable
Mahnaz Shoghi, Email: shoghi.m@iums.ac.ir
What processes are involved for a request to access data/document
After sending a request to academic email, we will send our data files up to one week.
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