Efficacy of ginger in control of resistant symptom in hypothyroid patient’s under thyroid hormone replacement treatment

Determination of the effect of ginger diet on refractory symptoms in patients with hypothyroidism

A randomized, double-blind, placebo-controlled clinical trial

Sixty hypothyroid patients and 60 normal TSH population with inclusion criteria were divided into two groups of 30 with A and B using block 4 randomization method. Demographic information is recorded. Blood samples are taken for TG, CHOL, FBS, TSH tests. ThySRQ questionnaire is completed for all patients.Group A and C were then given ginger capsules (500 mg twice daily) and group B and D received placebo capsules for one month.After one month of treatment, each patient is re-evaluated by performing ThySRQ tests and recording data.

A patient with controlled thyroid dysfunction, who still complains of symptoms Serum TSH level should be between .5 -5 units Informed consent of patients to participate in the study Age range 20-60 years Body mass index 19-35. Pregnancy 2. Co-infection with other thyroid diseases 3. Any type of malignancy 4. Experience the courage of ginger 5. Liver and kidney failure 6. Diseases related to the hypothalamic pituitary pathway 7. With malabsorption disorders such as celiac disease, IBD, atrophic gastritis 8. Concomitant use of drugs such as phenobarbital, phenytoin, carbamazepine, rifampin, glucocorticoid, estrogen, raloxifene 9- caused by severe mental illness 10- Use warfarin and statins 11. Purpose of pregnancy

We have two groups of 60 low-functioning thyroid and a normal population, each divided into two subgroups of 30 each, given one capsule group containing ginger powder and the other with a placebo

Help control resistant symptoms in hypothyroid patients undergoing thyroid hormone replacement therapy, such as feeling weak, coldness, menstrual disorders, constipation, depression ...

Using a block size 4 block randomization method based on the list provided by Random Allocation software separately for each patient group.

The placebo is given to participants in a color and drug-like odor scheme, and none of the dispensing personnel, the laboratory, and the co-worker except the principal therapist know that each patient received the drug or the medication.