Comparison of the efficacy and side effects of oxytocin + misoprostol with methyl ergonovine (metergin) + misoprostol and misoprostol alone in the excretion of pregnancy products.

Effectiveness and Side Effects of Oxytocin + Misoprostol with Methyl Ergovin (Miginal) + Misoprostol and Misoprostol alone in disposal of of pregnancy products

Clinical trial with control group and parallel groups. blinded and randomised number of patients:90

After entering the study, patients were randomly divided into three groups. The first group was the control group and only misoprostol was administered. The second and third groups were treated as case groups with different regimes .in the second group misoprostol and oxytocin and in third group Misoprostol and metergine were administered respectively as a medicinal regimens for 3 days. After that ultrasound was performed to check the residual tissue. If the remaining tissue is re-observed in ultrasonography, the mentioned above drugs were repeated for 3 days. If the remaining tissue was repeated again we continued the mentioned drugs 3 days more, and if the remaining tissue was observed again, the patient will undergo surgery. This study was conducted at Jahrom University of Medical Sciences .Participants and Health and medical staff were kept blind from the beginning to the end of the study

inclusion criteria: Willingness to outpatient treatment to dispose of pregnancy products gestational age less than 14 weeks no history of any high risk disease exclusion criteria: Intolerance to drug treatment Fatigue from the treatment process and unwillingness to continue the study

Patients were randomly divided into three groups. The first group was the control group and they were given only misoprostol. The second and third groups were treated with different regimens. The second group received misoprostol and oxytocin and the third group received misoprostol and metergin as medication.

time of disposal of pregnancy products

In this study, simple randomization method will be used, the randomization unit will be individualized and we will use random number table method to generate random sequence.People are divided into three groups (two case and one control group) . They also pack medication based on codes and another person who is unaware of the randomization process gives the drugs to the patients according to the mentioned codes .This randomization and allocation will be remained hidden from researchers and participants until the statistical analysis is completed.

despite obtaining written consent from patients to participate in the study, they only knew that they would participate in the study to find the best way to get rid of pregnancy products after first trimester abortion, but they did not know which group of drugs was included in the drug coding (one-way blinding).the ampoules and tablets were presented to the researchers in similar syringes and covers respectively (with special codes ) so that it could not be identified for the researchers. Accordingly, the researchers who assisted patients in prescribing the drug, although they knew what the drug's content was in each package, were unaware of the research hypotheses, so they did not know which intervention group and which control group to use , It should be noted that the participants in each group were unaware of the drug regime of the opposite group.(double-blinding). And because the drugs were prescribed to patients with a coding system, the researcher did not know when the data was analyzed until the final calculations were performed. Because the researcher knew about the coding system and the researchers did not know about this system, but the data reached the researcher with numbers 1, 2 and 3, so the researcher did not know until the end of the analysis and before generalizing the calculations to the groups that the numbers one and Two or three belong to which codes A, B and C. It is obvious that the researcher's help wrote down the numbers belonging to the codes somewhere and gave them to the researcher after analyzing the data. In this research, three-way blinding technique was found. Coding system: control group: a, second group: b, third group: c (when delivering drug envelopes coded by the researcher with the help of the researcher) Group naming system with numbers: control group: 1, second group: 2, third group: 3 (when delivering data on therapeutic effects and side effects by the researcher to the researcher) Note: Research Assistant for Researcher after Data Analysis: Control Group: A-1, Second Group: B-2, Third Group C-3.

data would be presented according to the jahrom university of medical sciences protocols

according to the jahrom university of medical sciences protocols

according to the jahrom university of medical sciences protocols

according to the jahrom university of medical sciences protocols

jahrom university of medical sciences

according to the jahrom university of medical sciences protocols