Protocol summary

Study aim
A comparison of the effect of Tamsulosin and Placebo in the treatment of urinary tract disorder in women
Design
Clinical trial, community based, parallel group, double blind, randomised controlled trial
Settings and conduct
This study was conducted in Tabriz Hospital and participants through simple randomization divided into intervention and control groups, and double blind study.
Participants/Inclusion and exclusion criteria
Inclusion criteria: women with at least three months urination problems; age between 18 to 65 years old; signing informed consent form. Exclusion criteria: active urinary tract infection; history of neurological disorders; pregnant women.
Intervention groups
Intervention group percieve tamsulosin and control group percieve placebo
Main outcome variables
Prevention of urinary retention and urinary complications

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20200111046086N1
Registration date: 2020-03-31, 1399/01/12
Registration timing: registered_while_recruiting

Last update: 2020-03-31, 1399/01/12
Update count: 0
Registration date
2020-03-31, 1399/01/12
Registrant information
Name
Changiz Naseri
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 41 3334 7054
Email address
ch.naseri@yahoo.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-08-23, 1398/06/01
Expected recruitment end date
2021-03-20, 1399/12/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
A comparison of the effect of Tamsulosin and placebo in the treatment of urinary tract disorder in women
Public title
Tamsulosin for treatment of urinary tract disorder in women
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Women with at least three months of urinary tract disorder Age between 18 to 65 years old Signing informed consent form
Exclusion criteria:
Active urinary tract infection History of neurological disorders Pregnant women
Age
From 18 years old to 65 years old
Gender
Female
Phase
2-3
Groups that have been masked
  • Participant
  • Outcome assessor
Sample size
Target sample size: 252
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
This is a double-blinded study and researcher and patients are kept unaware of intervention in each group and In order to allocation concealment, the type of intervention will be written on paper and placed in numbered, matte and packed envelopes.The envelopes will be opened in the order of participation of the participants and the type of group will be determined.
Placebo
Used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee Of Tabriz University Of Medical Sciences.
Street address
Third Floor, Central Building of Number2, Golgasht Street
City
Tabriz
Province
East Azarbaijan
Postal code
33357313
Approval date
2020-01-06, 1398/10/16
Ethics committee reference number
IR.TBZMED.REC.1398.1056

Health conditions studied

1

Description of health condition studied
Retention of urine
ICD-10 code
Retention
ICD-10 code description
R33

Primary outcomes

1

Description
Urinary symptoms (urgency; frequency; nocturia; dysuria; incomplete emptying)
Timepoint
1 Weeks after intervention
Method of measurement
Standard questionnaire (USSQ)

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: Tamsulosin capsule with a dose of 0.4 mg made in Iran, one daily for a maximum of 4 weeks
Category
Treatment - Drugs

2

Description
Control group: placebo capsule made in Iran, one daily for a maximum of 4 weeks
Category
Placebo

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam Reza educational and treatment center
Full name of responsible person
Changhis Naseri
Street address
Department of Urology,Imam Reza educational and treatment center, Golgasht Street, Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 7054
Email
Ch.naseri@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Dr Mohsen Mohammad Rahimi
Street address
Central building of Tabriz University of Medical Sciences, Golgasht avenue, Azadi street
City
Tabriz
Province
East Azarbaijan
Postal code
5156954567
Phone
+98 41 3335 5921
Email
mm.rahimi1357@gmail.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tabriz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Sakineh Haj Eebrahimi
Position
Pprofessor of Urology, Fellowship in Female Urology
Latest degree
Subspecialist
Other areas of specialty/work
Urology
Street address
Department of Urology, Imam Reza educational and treatment center, Golgasht Street, Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 7054
Email
hajebrahimis@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Sakineh Hajebrahimi
Position
Professor of Urology, Fellowship in Female Urology
Latest degree
Subspecialist
Other areas of specialty/work
Urology
Street address
Department of Urology, Imam Reza educational and treatment center, Golgasht Street, Tabriz
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 7054
Email
hajebrahimis@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Tabriz University of Medical Sciences
Full name of responsible person
Sakineh Haj Eebrahimi
Position
Professor of Urology, Fellowship in Female Urology
Latest degree
Subspecialist
Other areas of specialty/work
Urology
Street address
Department of Urology, Imam Reza educational and treatment center, Golgasht Street
City
Tabriz
Province
East Azarbaijan
Postal code
5166614766
Phone
+98 41 3334 7054
Email
hajebrahimis@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
A portion of the data that represents the final outcome
When the data will become available and for how long
Access will be 6 months after the results are printed.
To whom data/document is available
All Physicians and residents of the department of Urology
Under which criteria data/document could be used
After obtaining permission from the deputy research of group
From where data/document is obtainable
Person responsible for scientific accountability of study
What processes are involved for a request to access data/document
First approved by the Research Vice-President
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