Evaluation the Effect of Oral Aloe Vera Administration on Fasting Plasma Glucose, Lipid Profile, Body Composition Components, Anthropometric Indices, and Blood Pressure Values in Patients with Diabetes Type 2

Determining the effect of consuming aloe vera food powder on fasting blood sugar, lipid profile, body indicators measurement, combination of body mass and blood pressure of patients with type 2 diabetes

Clinical trial with control group, with parallel, double-blind, randomized groups

In this randomized clinical trial, double blind study 60 individuals with type 2 diabetes participated. After obtaining the consent of the eligible people to participate in the study, at the beginning and end of the study, after 11 hours of fasting at night, blood samples were collected and demographic information, body measurement and food intake were obtained. The participants were randomly assigned to two intervention groups (aloe vera) and placebo for 8 weeks.

Inclusion criteria: 1) The desire to participate in the study 2) Age range 18 to 69 years 3) Diagnosis of type 2 diabetes by a specialist 4) Duration of type 2 diabetes, at least 6 months 5) Having stable weight over the past 6 months( Self-report) 6) The type and dose of drugs used to be stable in the last 6 months Exclusion criteria 1) No Allergy to aloe vera or products containing it 2) No pregnancy and breastfeeding 9) No using any food supplement in the last 6 months 3) No smoking and being addicted 4) NO acute heart disease, stroke, liver, kidney, gastrointestinal, thyroid and parathyroid, rheumatoid and infectious arthritis

One group was given an oral aloe vera powder and the other group was given an oral tost flour

The oral effects of aloe vera on fasting glucose, triglycerides and weight, body mass index, abdominal circumference and systolic blood pressure were investigated in people with type 2 diabetes.

The allocation of participants in two groups of intervention and control is done by the Balanced block randomization method. (Randomization of people between the two groups will be done by blocking method. Thus, the size of the blocks is considered to be 4 and all possible cases are written for groups A and B, and this will be done until the number reaches 60 people.) It is repeated. Then, using a table of random numbers, each of the components of the blocks is given a number. The numbers given to each of the components of the blocks represent the number intended for each person that has already been determined. So the order of the group assigned to each person is specified).

Study participants, researchers, and assistants did not know who was in the intervention group and who was in the placebo group. The person who checked the information did not know which group the person belonged to, and the person who delivered the drugs did not know which group was interfering and knew groups 1 and 2. In addition, for weekly follow-ups, the first person was in contact with people who did not know in which group the person was. Participants did not know from the beginning to the end of study which group they were in.

The Excel file contains all the data

Start the access period 6 months after printing the results

Data will only be available to researchers working at academic and scientific institutions

Get permission before using the project executor

Dr. Siavash Baba Jafari: jafaris@sums.ac.ir Najmeh Sadat Zareian Jahromi: najmeh.zareayan@gmail.com

The applicant will introduce himself in an email and explain the reason for the need for data.   After review, the data will be sent within a week if agreed.