Comparison of the effect of interautal administration of bupivacaine and dextrose 5% and fentanyl on bupivacaine alone on the onset and duration of analgesia in patients undergoing lower limb orthopedic surgery

Comparison of the effect of interautal administration of bupivacaine and dextrose 5% and fentanyl on bupivacaine alone on the onset and duration of analgesia in patients undergoing lower limb orthopedic surgery

Clinical trial with control group, with parallel group; Double blind, randomized

This study is being performed at Imam Reza Hospital in Birjand, South Khorasan Province. 40 patients are randomly divided into two intervention groups, one and two. After anesthesia in patients and interventions related to each group, the amount of pain in each group at 0, 6, 12 and 24 hours after surgery, patients' blood pressure, heart rate and duration of pain by the nurse in the evaluation department will be.

Inclusion criteria include: having informed consent, patients with ASA class one and two, age between 20 and 50 years, no drug addiction, no spinal history following surgery in the past week, no pregnancy, no brain trauma. The most recent is spinal deformity. Exclusion criteria include: patients' dissatisfaction to continue studying, duration of surgery more than 1 hour, inability to position the patient, spinal infection, sensitivity to local anesthetic drugs, high ICP and coagulation disorders.

The first group under spinal by prescribing marcain 0.5% to 2 cc (10 mg) and the second group under spinal by prescribing marcain 0.5% 1 cc (5 mg) + 25 micrograms fentanyl (cc 0.5) + 0.5 cc of 5% sterile dextrose.

the pain Painless duration blood pressure heart beat

Individuals in each group will be randomly randomized and blocked, including spinal patients with a marcain prescription of 0.5% to cc 2 (10 mg) of group A, and the second group of spinal cord group B with a spinal margin prescription of 5 marcain. %0.5 cc 1 (mg 5) + micg 25 fentanyl (cc 0.5) + cc 0.5 dextrose will be 5% sterile. First, a variety of four blocks are created (AABB, BBAA, ABAB, BABA, ABBA, and BABA). Randomly one of these blocks is selected and patients will be divided into A or B by one of two surgical groups. Then the same is done for other patients.

Study participants without knowledge of the drug received for pain relief. Outcome Assessor: The ward nurse questions patients from patients without knowing the type of medication they are taking and registers them in the relevant checklist.

There is no need to publish individual patient information