The effect of pomegranate juice (no added sugar) consumption on lipid profile, inflammation factor and oxidative stress in overweight or obese patients with type 2 diabetes
The aim of this randomized double blind clinical trial is to determine the effects of pomegranate juice on some blood biochemical parameters in type 2 diabetic patients. Fifty patients aged between 30-50 years old from both sexes are assigned into two groups. Patients in intervention group consume 250ml/day pomegranate juice and patients in control group consume 250ml/day water for 8 weeks. Anthropometric and blood pressure measurements,3 times 3-day food record and fasting blood samples are collected at the beginning and at the end of study. Fasting blood sugar, glycosylated hemoglobin, insulin, lipid profile, malondialdehyde (MDA), total antioxidant capacity (TAC), superoxide dismutase, glutathione peroxidase and hsCRP are measured. LDL and HOMA-IR are calculated by formula. The participants are asked not to change their regular diet, medicine and activity during the study.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT138904294424N1
Registration date:2010-10-18, 1389/07/26
Registration timing:retrospective
Last update:
Update count:0
Registration date
2010-10-18, 1389/07/26
Registrant information
Name
Samira Babayian Amini
Name of organization / entity
Tabriz university of medical sciences
Country
Iran (Islamic Republic of)
Phone
+98 914 407 5580
Email address
ebrahimiemamagani@tbzmed.ac.ir
Recruitment status
Recruitment complete
Funding source
Nutrition research center, Tabriz University of Medical Sciences & Shadli Company
Expected recruitment start date
2010-05-31, 1389/03/10
Expected recruitment end date
2010-08-01, 1389/05/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of pomegranate juice (no added sugar) consumption on lipid profile, inflammation factor and oxidative stress in overweight or obese patients with type 2 diabetes
Public title
The effects of pomegranate juice on type 2 diabetes
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria: male or female, 30 to 50 years old, BMI between 25-35, having type 2 diabetes at least 6 month, taking metformin or glybanclamid, taking atrovastain, simvastatin or levostatin. Exclusion criteria: having the renal or hepatic failure, treatment With HRT, smoking, treatment with insulin, use of multivitamin-mineral 6 months prior to the study.
Age
From 30 years old to 50 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
50
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Tabriz University of Medical Sciences