Evaluation of sedative effect of thyme on cough in children 5 to 12 years of age with asthma

Evaluation of the sedative effect of thyme in cough in children with asthma

In this double-blind clinical trial, phase 2, 60 children with asthma who have the inclusion criteria are placed in 2 parallel groups of 30 patients using a table of random numbers

In this study, 60 children with asthma aged 5 to 12 years who referred to the allergy clinic of Ardabil University of Medical Sciences were randomly divided into two groups (30 patients in each group). After obtaining written consent from the parents, general information and cough and fever, wheezing and other symptoms of respiratory infection will be collected. Patients in the intervention group will be given 1 to 4 grams of dried thyme leaf powder prepared as a syrup for a week, at a dose of 20 mg / kg every 8 hours along with routine medical treatment, and the control group will receive routine medical treatment and 2 cc placebo syrup .

Having asthma, age between 5-12 years, Lack of chronic disability or illness. Exclusion criteria: Failure to complete the course of treatment

Intervention group: Patients in the intervention group will be given 1 to 4 grams of dried thyme leaf powder prepared as a syrup for a week, at a dose of 20 mg / kg every 8 hours, along prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co) with routine medical treatment.. Control group: The control group will receive 2 cc placebo syrup and prednisolone tablets (1 mg / kg, daily, Abureyhan Co.), salbutamol spray (2 puffs every 3 hours by Caspian Tamin Co), theophylline syrup (4 cc every 6 hours by Elixir Co).

cough

Incomplete number of patients

Randomization method is a simple randomizing using a table of random numbers, a set of numbers which is completely generated randomly without any specific pattern or order in a table form. Table numbers are read from the left, in a way that even numbers are assigned to intervention A and odd numbers to intervention B. In this way, the researcher touches one of the numbers and moves to the right, then records the numbers and assigns them to different groups. Next, considering the volume of the research sample, aluminum wrapper envelopes are prepared (in order not to clarify the content of the envelopes), each of the random sequences is recorded on a card and placed inside an envelope. To maintain a random sequence, envelopes are numbered in the same way. Finally, the flap of the envelopes are sealed and respectively placed inside a box. To reveal the participants' assigned group, at the beginning of the registration based on the order of eligible participants entry to study, one of the envelopes is opened.

Due to the fact that placebo is used, patients and outcome assessors are unaware of the type of intervention.