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Study aim
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Evaluate the effects of a low free sugar diet on lipid profile, glycemic indices, liver enzymes, inflammatory factors and hepatic steatosis and fibrosis in patients with Nonalcoholic fatty liver disease.
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Design
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Randomized clinical trials with control groups, parallel groups are performed on 42 patients.
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Settings and conduct
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In this study, adults with non-alcoholic fatty liver disease referred to Taleghani Hospital's Liver Clinic, who have the criteria to enter the study, if they desire to participate in this research with steatosis in ultrasound or fibroscan; general and activity questionnaires, anthropometric indicators are collected. At the beginning and end of the study, fibroscan and blood tests will be performed to evaluate the indicators.
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Participants/Inclusion and exclusion criteria
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People who desire to participate in the study with age 18-60 years and BMI above 20 who have evidence of non-alcoholic steatohepatitis in ultrasound or fibroscan and no history of alcohol consumption or Alcohol consumption less than 10 grams per day in women and less than 20 grams per day in men in the absence of other chronic and acute liver diseases and disorders, biliary tract disease, autoimmune diseases, cancer and hereditary disorders affecting Liver status and liver cirrhosis, lack of pregnancy or lactation in women, and non-use of hepatotoxic drugs are included in the study, and if they do not want to continue studying or using hepatotoxic drugs during the study or non-compliance with the diet, they will be excluded.
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Intervention groups
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Each person is randomly assigned to a low free sugar diet or a regular diet group with a dietary recommendation based on the classification.
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Main outcome variables
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Hepatic fibrosis, and steatosis
Lipid profile, Glycemic indices, Liver enzymes, Inflammatory factors