Evaluation of treatment of chronic constipation using combination of Rosa damascene and brown sugar in comparison with polyethylene glycol in children over 12 months old

Comparison of the effect of using the combination of Mohammadi red rose and red sugar with polyethylene glycol in the treatment of constipation in children over 12 months in Shiraz

Clinical trial with control group, with cross-groups, double-blind, randomized, phase 2 on 100 patients. Block randomization has been used.

In this study, based on a pilot project and two blind heads, 100 children over 12 months referred to Imam Reza Specialized and Subspecialty Clinic of Shiraz University of Medical Sciences, who were diagnosed with Functional Chronic Constipation based on their history and physical examination. They will be investigated after obtaining informed consent from the parents.

Admission: Children over 12 months of age with Functional Constipation with Conscious Parental Satisfaction Withdrawal: Patients who have an underlying disease such as hypothyroidism based on the history and physical examination

In the test group, 50 children used the combination of Mohammadi rose and red sugar as a treatment for constipation, and in the control group of 50 children, they used polyethylene glycol as a treatment for constipation.

Defecation less than or equal to two times a week, Fecal incontinence equal or more than once a week, History of excessive stool retention, History of hard or painful defecation, Large fecal mass in the rectum, History of thick stools that may block the toilet, Appetite disorder, Bad Breath, Abdominal pain

Eligible people in the study will be randomly assigned to two groups based on a double-blind study. The random allocation will be blockchain,Four-person blocks that we will have 25 blocks. Twenty-five blocks of four people are selected with random allocation software and people will be assigned to two groups based on these blocks.

In this double-blind study, polyethylene glycol syrup in the control group and rose + red sugar syrup based on the evidence of traditional medicine with great effect in the treatment of constipation in the experimental group was used. For this purpose, new patients referred to Imam Reza Clinic of Shiraz University of Medical Sciences After examining and diagnosing constipation, the doctor writes the title of the medicine to treat constipation on the prescription sheet. The patient's initial information is recorded by staff who are also blind, and then the patient is referred to the clinic pharmacy for medication. There, the pharmacy staff, who are blind, give the patient a drug coded by the pharmacist based on a four-item random block table.

After the research and publication of the article, information about the main outcome and the interventions will be shared.

At the end of the study since 2021

All physicians and researchers related to the field of pediatrics

For therapeutic and research use, information will be provided to all physicians and researchers

Shiraz Namazi Hospital, Pediatric's Department Office, Pediatric Gastroenterology Department

By referring to Shiraz Namazi Hospital, Pediatric's Department Office, Pediatric Gastroenterology Department