Comparison of the Effectiveness of Nasal Ketamine vs. Intravenous (IV) Ketamine in anesthesia in Patients with Cataract Surgery

Comparison of the Effectiveness of Nasal Ketamine vs. Intravenous Ketamine in analgesia in Patients with Cataract Surgery

Randomised, superiority, parallel, three-way blind, randomized, on 90 patients. Randomisation was centralised and computerised with concealed randomisation sequence carried out at an external site

This study was a three-course study conducted at the Feyz Isfahan Medical-Educational Center. The available (easy) sampling method and simple randomization method were used using Random allocation software. The patient surgeon and the person collecting the information were unaware of the patients' drug grouping

Candidates for Cataract Surgery in adults Criteria for not entering the study: history of allergy or allergic reaction to any of the medications of diet therapy, head injury, high intraocular or intracranial pressure, high-risk cardiovascular disease, hypertension, severe respiratory disease, liver disease, advanced Epilepsy or history of seizures, neurological disorders, tumors or brain metastases, use of any painkillers and anesthesia precursors, chronic pain syndromes, people who are not satisfied with participating in this study

In Intravenous ketamine group, (1 mg / kg with a volume of 3 cc ketamin) is prescribed intravenously and 3 cc of distilled water in the nose. In the nasal ketamine group, 3 cc of ketamine, 1 mg / kg intranasaly, and 3 cc of distilled water are administered intravenously.

Nasal Ketamin

The 45 pieces of paper that were written on it A and the other 45 pieces that were written B (a total of 90 pieces) are folded into a non-transparent bag. Then 30 minute before the operation, one of the pieces were selected randomly by a person who does not know about the details. In case of A patient categorized as the intera-venous Ketamine group, and in case of B, it belongs to the nasal Ketamine group.

Patient, surgeon and data collector