Comparison of the Effectiveness of Nasal fentanyl vs. Intravenous (IV) fentanyl in anesthesia in patients with cataract surgery

Comparison of the Effectiveness of Nasal fentanyl vs.Intravenous fentanyl in analgesia in patients with cataract surgery

Randomised, superiority, parallel, three-way blind, randomized, on 90 patients.Randomisation was centralised and computerised with concealed randomisation sequence carried out at an external site

This study was a three-course study conducted at the Feyz Isfahan Medical-Educational Center. The available (easy) sampling method and simple randomization method were used using Random allocation software. The patient surgeon and the person collecting the information were unaware of the patients' drug grouping

Candidates for cataract surgery in adults Criteria for not entering the study: history of allergy or allergic reaction to any of the medications of diet therapy, head injury, high intraocular or intracranial pressure, high-risk cardiovascular disease, hypertension, severe respiratory disease, liver disease, advanced Epilepsy or history of seizures, neurological disorders, tumors or brain metastases, use of any painkillers and anesthesia precursors, chronic pain syndromes, people who are not satisfied with participating in this study

in Intravenous fentanyl group, (1.5 mg / kg with a volume of 2 cc fentanyl) is prescribed intravenously and 2 cc of distilled water in the nose. In the nasal fentanyl group, 2cc of fentanyl, 1.5 mg / kg intranasaly, and 2 cc of distilled water are administered intravenously.

Intravenous fentanyl؛ Intranasal fentanyl

The 45 pieces of paper that were written on it A and the other 45 pieces that were written B (a total of 90 pieces) are folded into a non-transparent bag. Then 30 minute before the operation, one of the pieces were selected randomly by a person who does not know about the details. In case of A patient categorized as the intera-venous fentanyl group, and in case of B, it belongs to the nasal fentanyl group.

In 30 minute before the surgery, the patient was selected to A and B group by using pieces of paper in a non-transparent bag by person who did not know about the details. The patient didnt know about the grouping. The patient was taken to the operating room and the surgeon and staff of the relevant room did not know about the grouping. After the surgery, the surgeon's satisfaction was recorded by the person who did not know about the grouping. The patient transferred to the recovery room, where was evaluated by the person who had no information about the grouping and the patient's information was recorded. In the operating room, only the person who performed the lottery knew about the grouping, and this person had intravenous and nasal fentanyl in addition to distilled water in the form of nasal and intravenous form, and he was the only person who knew which fentanyl and which distilled water were also. This person was not present in any other part of the patient's information collection and evaluation