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Study aim
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Comparison of postoperative outcomes of prone, semi-prone and lateral decubitus positions in thoracoscopic-laparoscopic esophagectomy of patients with esophageal cancer referred to Imam Reza hospital between 2018-2020
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Design
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A clinical trial with 3 groups, randomized, single-blind, on 51 patients using simple random sampling method.
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Settings and conduct
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In this clinical trial study, 51 patients with cancer referred to Imam Reza (AS) hospital in Tabriz between 2018-2020, who are willing to undergo upper endoscopy and biopsy and approved, will be included in the study. Staging and surgical intervention in patients will be performed by CT-Scan with chest and abdomen contrast and bronchoscopy (for middle third tumors). For all Chest X-Ray patients, lung function tests, ECG and cardiovascular function will be performed. The surgeon will not know the type of position before entering the operating room, and upon entering the operating room, the relevant nurse will randomly announce the type of surgical position to the surgeon based on the list prepared and those who evaluate the consequences of surgery will not know the type of position and goals of the study.
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: Satisfaction to participate in the study and esophageal cancer
Exclusion criteria: Sensitivity to anesthetics and impossibility of anesthesia and death of the patient during surgery
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Intervention groups
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Patients will be randomly divided into 3 groups: prone position, semi-prone position and lateral decubitus. Patients will then undergo MIE.
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Main outcome variables
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Intraoperative variables (duration of surgery, rate of blood loss, likelihood of change to open surgery) and postoperative variables (mortality, morbidity: respiratory complications, esophagogastric anastomotic leakage, thoracic duct injury, hoarseness)