Evaluation of the effect of adding oral vial L-carnitine on the efficacy of sildenafil citrate tablets in the treatment of erectile dysfunction in men with type 2 diabetes

Determining the effect of adding oral vial L-carnitine on the efficacy of sildenafil citrate tablets in the treatment of erectile dysfunction in men with type 2 diabetes

This study is a double-blind randomized clinical trial with parallel groups that is performed in phase 3 clinical trial on 40 diabetic patients with erectile dysfunction. For randomization in this study, block randomization method with proportional number and software was performed.

This study is performed in 40 diabetic patients with erectile dysfunction in Imam Reza Clinic in Arak. Patients are not aware of the type of medication they are taking and For the control group, an oral L-carnitine placebo vial made by the same company was used. Also the intern in charge of the project who is responsible for filling out the questionnaire; He is not aware of the type of groups according to the drug used and only recognizes the groups based on A and B, and the form of demographic information and the International Erectile Dysfunction Questionnaire 5 (IIEF5) are completed for both groups. 4 weeks later, patients' erectile function will be evaluated again.

Erectile dysfunction; diagnosis of type 2 diabetes; age 40 to 70 years old; no spinal cord injury

In the intervention group, sildenafil citrate tablets in the amount of 100 mg half an hour before sexual intercourse with oral vial of carnitine alone or dissolved in a drink or liquid food at a rate of 1 g per day is used and the second group (control group) will also be treated with sildenafil citrate 100 mg half an hour before each sexual intercourse with an oral placebo vial. After 4 weeks, the International Erectile Dysfunction Questionnaire 5 (IIEF5) will be completed again in similar circumstances.

Erectile function

In this study, 40 male patients with type 2 diabetes referred to Imam Reza (AS) Diabetes Clinic who complain of erectile dysfunction and this disorder has been approved by a urologist who collaborated with the project, if they have the conditions to enter the study and Using block randomization method and using software are divided into two groups of intervention and control

Blindness, due to its double blindness, is such that in this study, only the specialist in charge of the study is aware of the type of study and the study groups, while patients are not aware of the type of drug used. Also, the intern in charge of the project who is responsible for filling out the questionnaire; He is not aware of the type of groups according to the drug used and only recognizes the groups based on A and B, and the form of demographic information and the International Erectile Dysfunction Questionnaire 5 (IIEF5) are completed for both groups. Patients are randomly divided into intervention and control groups, and both groups receive sildenafil tablets, but the intervention group receives vials of L-carnitine and the placebo control group receives the same vial of L-carnitine, both of which are manufactured by BSK Bio-Fermentation. .receive sildenafil tablets, but the intervention group is vial L-carnitine and the placebo control group is similar to vial L-carnitine, both of which are manufactured by B. They receive bio-fermentation.